2uxx

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m (Protected "2uxx" [edit=sysop:move=sysop])
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[[Image:2uxx.png|left|200px]]
[[Image:2uxx.png|left|200px]]
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{{STRUCTURE_2uxx| PDB=2uxx | SCENE= }}
{{STRUCTURE_2uxx| PDB=2uxx | SCENE= }}
===HUMAN LSD1 HISTONE DEMETHYLASE-COREST IN COMPLEX WITH AN FAD-TRANYLCYPROMINE ADDUCT===
===HUMAN LSD1 HISTONE DEMETHYLASE-COREST IN COMPLEX WITH AN FAD-TRANYLCYPROMINE ADDUCT===
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{{ABSTRACT_PUBMED_17569509}}
{{ABSTRACT_PUBMED_17569509}}
==About this Structure==
==About this Structure==
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[[2uxx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXX OCA].
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[[2uxx]] is a 2 chain structure of [[Lysine-specific histone demethylase 1]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXX OCA].
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==See Also==
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*[[Lysine-specific histone demethylase 1|Lysine-specific histone demethylase 1]]
==Reference==
==Reference==
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<ref group="xtra">PMID:17569509</ref><ref group="xtra">PMID:16885027</ref><references group="xtra"/>
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<ref group="xtra">PMID:017569509</ref><ref group="xtra">PMID:016885027</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Cole, P A.]]
[[Category: Cole, P A.]]
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[[Category: Yang, M.]]
[[Category: Yang, M.]]
[[Category: Yu, H.]]
[[Category: Yu, H.]]
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[[Category: Alternative splicing]]
 
[[Category: Chromatin demethylation]]
[[Category: Chromatin demethylation]]
[[Category: Chromatin regulator]]
[[Category: Chromatin regulator]]
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[[Category: Coiled coil]]
 
[[Category: Corest]]
[[Category: Corest]]
[[Category: Depression]]
[[Category: Depression]]
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[[Category: Nucleosome]]
[[Category: Nucleosome]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase/repressor]]
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[[Category: Oxidoreductase-repressor complex]]
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[[Category: Oxidoreductase/repressor complex]]
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[[Category: Phosphorylation]]
[[Category: Phosphorylation]]
[[Category: Repressor]]
[[Category: Repressor]]

Revision as of 09:46, 25 July 2012

Image:2uxx.png

Template:STRUCTURE 2uxx

Contents

HUMAN LSD1 HISTONE DEMETHYLASE-COREST IN COMPLEX WITH AN FAD-TRANYLCYPROMINE ADDUCT

Template:ABSTRACT PUBMED 17569509

About this Structure

2uxx is a 2 chain structure of Lysine-specific histone demethylase 1 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Yang M, Culhane JC, Szewczuk LM, Jalili P, Ball HL, Machius M, Cole PA, Yu H. Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine. Biochemistry. 2007 Jul 10;46(27):8058-65. Epub 2007 Jun 15. PMID:17569509 doi:10.1021/bi700664y
  • Yang M, Gocke CB, Luo X, Borek D, Tomchick DR, Machius M, Otwinowski Z, Yu H. Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase. Mol Cell. 2006 Aug 4;23(3):377-87. PMID:16885027 doi:http://dx.doi.org/10.1016/j.molcel.2006.07.012

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OCA

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