2b8l

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Revision as of 09:52, 25 July 2012

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Template:STRUCTURE 2b8l

Contents 1 Crystal structure of human beta secretase complexed with inhibitor 2 About this Structure 3 See Also 4 Reference

Crystal structure of human beta secretase complexed with inhibitor

Template:ABSTRACT PUBMED 16263281

About this Structure

2b8l is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Beta secretase

Reference

• Stachel SJ, Coburn CA, Steele TG, Crouthamel MC, Pietrak BL, Lai MT, Holloway MK, Munshi SK, Graham SL, Vacca JP. Conformationally biased P3 amide replacements of beta-secretase inhibitors. Bioorg Med Chem Lett. 2006 Feb;16(3):641-4. Epub 2005 Nov 2. PMID:16263281 doi:10.1016/j.bmcl.2005.10.032