3pd8
From Proteopedia
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[[Image:3pd8.png|left|200px]] | [[Image:3pd8.png|left|200px]] | ||
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===X-ray structure of the ligand-binding core of GluA2 in complex with (S)-7-HPCA at 2.5 A resolution=== | ===X-ray structure of the ligand-binding core of GluA2 in complex with (S)-7-HPCA at 2.5 A resolution=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Ionotropic Glutamate Receptors]] | + | *[[Ionotropic Glutamate Receptors|Ionotropic Glutamate Receptors]] |
==Reference== | ==Reference== | ||
Revision as of 09:58, 25 July 2012
Contents |
X-ray structure of the ligand-binding core of GluA2 in complex with (S)-7-HPCA at 2.5 A resolution
Template:ABSTRACT PUBMED 21067182
About this Structure
3pd8 is a 3 chain structure of Ionotropic Glutamate Receptors with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
See Also
Reference
- Frydenvang K, Pickering DS, Greenwood JR, Krogsgaard-Larsen N, Brehm L, Nielsen B, Vogensen SB, Hald H, Kastrup JS, Krogsgaard-Larsen P, Clausen RP. Biostructural and Pharmacological Studies of Bicyclic Analogues of the 3-Isoxazolol Glutamate Receptor Agonist Ibotenic Acid. J Med Chem. 2010 Nov 10. PMID:21067182 doi:10.1021/jm101218a
- Hogner A, Kastrup JS, Jin R, Liljefors T, Mayer ML, Egebjerg J, Larsen IK, Gouaux E. Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core. J Mol Biol. 2002 Sep 6;322(1):93-109. PMID:12215417
- Armstrong N, Gouaux E. Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron. 2000 Oct;28(1):165-81. PMID:11086992
