1af9
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1af9" size="450" color="white" frame="true" align="right" spinBox="true" caption="1af9, resolution 2.7Å" /> '''TETANUS NEUROTOXIN C ...) |
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| - | [[Image:1af9.jpg|left|200px]]<br /><applet load="1af9" size=" | + | [[Image:1af9.jpg|left|200px]]<br /><applet load="1af9" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1af9, resolution 2.7Å" /> | caption="1af9, resolution 2.7Å" /> | ||
'''TETANUS NEUROTOXIN C FRAGMENT'''<br /> | '''TETANUS NEUROTOXIN C FRAGMENT'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The 2.7 A structure of the tetanus neurotoxin receptor binding fragment Hc | + | The 2.7 A structure of the tetanus neurotoxin receptor binding fragment Hc reveals a jelly-roll domain and a beta-trefoil domain. Hc retains the unique transport properties of the holotoxin and is capable of eliciting a protective immunological response against the full length holotoxin. |
==About this Structure== | ==About this Structure== | ||
| - | 1AF9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_tetani Clostridium tetani]. Active as [http://en.wikipedia.org/wiki/Tentoxilysin Tentoxilysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.68 3.4.24.68] Full crystallographic information is available from [http:// | + | 1AF9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_tetani Clostridium tetani]. Active as [http://en.wikipedia.org/wiki/Tentoxilysin Tentoxilysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.68 3.4.24.68] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AF9 OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Tentoxilysin]] | [[Category: Tentoxilysin]] | ||
| - | [[Category: Furey, W | + | [[Category: Furey, W F.]] |
[[Category: Sax, M.]] | [[Category: Sax, M.]] | ||
| - | [[Category: Schmidt, J | + | [[Category: Schmidt, J J.]] |
[[Category: Swaminathan, S.]] | [[Category: Swaminathan, S.]] | ||
| - | [[Category: Umland, T | + | [[Category: Umland, T C.]] |
[[Category: Wingert, L.]] | [[Category: Wingert, L.]] | ||
[[Category: clostridial neurotoxin]] | [[Category: clostridial neurotoxin]] | ||
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[[Category: tetanus]] | [[Category: tetanus]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:43:54 2008'' |
Revision as of 09:43, 21 February 2008
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TETANUS NEUROTOXIN C FRAGMENT
Overview
The 2.7 A structure of the tetanus neurotoxin receptor binding fragment Hc reveals a jelly-roll domain and a beta-trefoil domain. Hc retains the unique transport properties of the holotoxin and is capable of eliciting a protective immunological response against the full length holotoxin.
About this Structure
1AF9 is a Single protein structure of sequence from Clostridium tetani. Active as Tentoxilysin, with EC number 3.4.24.68 Full crystallographic information is available from OCA.
Reference
Structure of the receptor binding fragment HC of tetanus neurotoxin., Umland TC, Wingert LM, Swaminathan S, Furey WF, Schmidt JJ, Sax M, Nat Struct Biol. 1997 Oct;4(10):788-92. PMID:9334741
Page seeded by OCA on Thu Feb 21 11:43:54 2008
