1tg2
From Proteopedia
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[[Image:1tg2.png|left|200px]] | [[Image:1tg2.png|left|200px]] | ||
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{{STRUCTURE_1tg2| PDB=1tg2 | SCENE= }} | {{STRUCTURE_1tg2| PDB=1tg2 | SCENE= }} | ||
===Crystal structure of phenylalanine hydroxylase A313T mutant with 7,8-dihydrobiopterin bound=== | ===Crystal structure of phenylalanine hydroxylase A313T mutant with 7,8-dihydrobiopterin bound=== | ||
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{{ABSTRACT_PUBMED_15557004}} | {{ABSTRACT_PUBMED_15557004}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Phenylketonuria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=612349 612349]], Hyperphenylalaninemia, mild OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=612349 612349]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1tg2]] is a 1 chain structure of [[Phenylalanine hydroxylase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TG2 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Phenylalanine hydroxylase|Phenylalanine hydroxylase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015557004</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Phenylalanine 4-monooxygenase]] | [[Category: Phenylalanine 4-monooxygenase]] | ||
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[[Category: Tyring, S.]] | [[Category: Tyring, S.]] | ||
[[Category: Ugarte, M.]] | [[Category: Ugarte, M.]] | ||
| - | [[Category: Phenylalanine hydroxylase phenylketonuria mutant a313t in complex with cofactor analogue 7 | + | [[Category: 8-dihydrobiopterin]] |
| - | + | [[Category: Oxidoreductase]] | |
| - | + | [[Category: Phenylalanine hydroxylase phenylketonuria mutant a313t in complex with cofactor analogue 7]] | |
Revision as of 10:55, 25 July 2012
Contents |
Crystal structure of phenylalanine hydroxylase A313T mutant with 7,8-dihydrobiopterin bound
Template:ABSTRACT PUBMED 15557004
About this Structure
1tg2 is a 1 chain structure of Phenylalanine hydroxylase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Erlandsen H, Pey AL, Gamez A, Perez B, Desviat LR, Aguado C, Koch R, Surendran S, Tyring S, Matalon R, Scriver CR, Ugarte M, Martinez A, Stevens RC. Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations. Proc Natl Acad Sci U S A. 2004 Nov 30;101(48):16903-8. Epub 2004 Nov 19. PMID:15557004
Categories: Homo sapiens | Phenylalanine 4-monooxygenase | Aguado, C. | Desviat, L R. | Erlandsen, H. | Gamez, A. | Koch, R. | Martinez, A. | Matalon, R. | Perez, B. | Pey, A L. | Scriver, C R. | Stevens, R C. | Surendran, S. | Tyring, S. | Ugarte, M. | 8-dihydrobiopterin | Oxidoreductase | Phenylalanine hydroxylase phenylketonuria mutant a313t in complex with cofactor analogue 7
