3c17
From Proteopedia
(Difference between revisions)
m (Protected "3c17" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
[[Image:3c17.png|left|200px]] | [[Image:3c17.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3c17", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3c17| PDB=3c17 | SCENE= }} | {{STRUCTURE_3c17| PDB=3c17 | SCENE= }} | ||
===Hexagonal Crystal Structure of Precursor E. coli Isoaspartyl Peptidase/l-Asparaginase (ECAIII) with Active-site T179A mutation=== | ===Hexagonal Crystal Structure of Precursor E. coli Isoaspartyl Peptidase/l-Asparaginase (ECAIII) with Active-site T179A mutation=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_18334484}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 18334484 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_18334484}} | {{ABSTRACT_PUBMED_18334484}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3c17]] is a 2 chain structure of [[Aminopeptidase]] with sequence from [http://en.wikipedia.org/wiki/ | + | [[3c17]] is a 2 chain structure of [[Aminopeptidase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C17 OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Aminopeptidase]] | + | *[[Aminopeptidase|Aminopeptidase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018334484</ref><ref group="xtra">PMID:015946951</ref><ref group="xtra">PMID:011053866</ref><ref group="xtra">PMID:016725155</ref><ref group="xtra">PMID:015159592</ref><ref group="xtra">PMID:010490104</ref><ref group="xtra">PMID:009545304</ref><ref group="xtra">PMID:009737998</ref><ref group="xtra">PMID:012906830</ref><ref group="xtra">PMID:007477383</ref><references group="xtra"/> |
| - | [[Category: Escherichia coli | + | [[Category: Escherichia coli]] |
[[Category: Hernandez-Santoyo, A.]] | [[Category: Hernandez-Santoyo, A.]] | ||
[[Category: Jaskolski, M.]] | [[Category: Jaskolski, M.]] | ||
| Line 32: | Line 21: | ||
[[Category: Asparaginase]] | [[Category: Asparaginase]] | ||
[[Category: Autoproteolysis]] | [[Category: Autoproteolysis]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Isoaspartyl peptidase]] | [[Category: Isoaspartyl peptidase]] | ||
[[Category: Ntn-hydrolase]] | [[Category: Ntn-hydrolase]] | ||
[[Category: Precursor]] | [[Category: Precursor]] | ||
Revision as of 11:03, 25 July 2012
Contents |
Hexagonal Crystal Structure of Precursor E. coli Isoaspartyl Peptidase/l-Asparaginase (ECAIII) with Active-site T179A mutation
Template:ABSTRACT PUBMED 18334484
About this Structure
3c17 is a 2 chain structure of Aminopeptidase with sequence from Escherichia coli. Full crystallographic information is available from OCA.
See Also
Reference
- Michalska K, Hernandez-Santoyo A, Jaskolski M. The mechanism of autocatalytic activation of plant-type L-asparaginases. J Biol Chem. 2008 May 9;283(19):13388-97. Epub 2008 Mar 10. PMID:18334484 doi:10.1074/jbc.M800746200
- Michalska K, Brzezinski K, Jaskolski M. Crystal structure of isoaspartyl aminopeptidase in complex with L-aspartate. J Biol Chem. 2005 Aug 5;280(31):28484-91. Epub 2005 Jun 9. PMID:15946951 doi:10.1074/jbc.M504501200
- Borek D, Jaskolski M. Crystallization and preliminary crystallographic studies of a new L-asparaginase encoded by the Escherichia coli genome. Acta Crystallogr D Biol Crystallogr. 2000 Nov;56(Pt 11):1505-7. PMID:11053866
- Michalska K, Bujacz G, Jaskolski M. Crystal structure of plant asparaginase. J Mol Biol. 2006 Jun 30;360(1):105-16. Epub 2006 May 15. PMID:16725155 doi:10.1016/j.jmb.2006.04.066
- Prahl A, Pazgier M, Hejazi M, Lockau W, Lubkowski J. Structure of the isoaspartyl peptidase with L-asparaginase activity from Escherichia coli. Acta Crystallogr D Biol Crystallogr. 2004 Jun;60(Pt 6):1173-6. Epub 2004, May 21. PMID:15159592 doi:10.1107/S0907444904003403
- Xu Q, Buckley D, Guan C, Guo HC. Structural insights into the mechanism of intramolecular proteolysis. Cell. 1999 Sep 3;98(5):651-61. PMID:10490104
- Guan C, Liu Y, Shao Y, Cui T, Liao W, Ewel A, Whitaker R, Paulus H. Characterization and functional analysis of the cis-autoproteolysis active center of glycosylasparaginase. J Biol Chem. 1998 Apr 17;273(16):9695-702. PMID:9545304
- Saarela J, Laine M, Tikkanen R, Oinonen C, Jalanko A, Rouvinen J, Peltonen L. Activation and oligomerization of aspartylglucosaminidase. J Biol Chem. 1998 Sep 25;273(39):25320-8. PMID:9737998
- Qian X, Guan C, Guo HC. A dual role for an aspartic acid in glycosylasparaginase autoproteolysis. Structure. 2003 Aug;11(8):997-1003. PMID:12906830
- Brannigan JA, Dodson G, Duggleby HJ, Moody PC, Smith JL, Tomchick DR, Murzin AG. A protein catalytic framework with an N-terminal nucleophile is capable of self-activation. Nature. 1995 Nov 23;378(6555):416-9. PMID:7477383 doi:http://dx.doi.org/10.1038/378416a0
