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3dxd
From Proteopedia
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[[Image:3dxd.png|left|200px]] | [[Image:3dxd.png|left|200px]] | ||
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{{STRUCTURE_3dxd| PDB=3dxd | SCENE= }} | {{STRUCTURE_3dxd| PDB=3dxd | SCENE= }} | ||
===Crystal structure of the intracellular domain of human APP (T668E mutant) in complex with Fe65-PTB2=== | ===Crystal structure of the intracellular domain of human APP (T668E mutant) in complex with Fe65-PTB2=== | ||
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{{ABSTRACT_PUBMED_18833287}} | {{ABSTRACT_PUBMED_18833287}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3dxd]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DXD OCA]. | + | [[3dxd]] is a 4 chain structure of [[Amyloid precursor protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DXD OCA]. |
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| + | ==See Also== | ||
| + | *[[Amyloid precursor protein|Amyloid precursor protein]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018833287</ref><ref group="xtra">PMID:018453713</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Radzimanowski, J.]] | [[Category: Radzimanowski, J.]] | ||
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[[Category: Wild, K.]] | [[Category: Wild, K.]] | ||
[[Category: Aicd]] | [[Category: Aicd]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Alzheimer disease]] | [[Category: Alzheimer disease]] | ||
[[Category: Alzheimer's disease]] | [[Category: Alzheimer's disease]] | ||
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[[Category: Cell adhesion]] | [[Category: Cell adhesion]] | ||
[[Category: Coated pit]] | [[Category: Coated pit]] | ||
| - | [[Category: Copper]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Endocytosis]] | [[Category: Endocytosis]] | ||
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[[Category: Notch signaling pathway]] | [[Category: Notch signaling pathway]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease inhibitor]] | [[Category: Protease inhibitor]] | ||
[[Category: Protein binding]] | [[Category: Protein binding]] | ||
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[[Category: Serine protease inhibitor]] | [[Category: Serine protease inhibitor]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
| - | [[Category: Zinc]] | ||
Revision as of 11:45, 25 July 2012
Contents |
Crystal structure of the intracellular domain of human APP (T668E mutant) in complex with Fe65-PTB2
Template:ABSTRACT PUBMED 18833287
About this Structure
3dxd is a 4 chain structure of Amyloid precursor protein with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Radzimanowski J, Simon B, Sattler M, Beyreuther K, Sinning I, Wild K. Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2. EMBO Rep. 2008 Nov;9(11):1134-40. Epub 2008 Oct 3. PMID:18833287 doi:http://dx.doi.org/10.1038/embor.2008.188
- Radzimanowski J, Beyreuther K, Sinning I, Wild K. Overproduction, purification, crystallization and preliminary X-ray analysis of human Fe65-PTB2 in complex with the amyloid precursor protein intracellular domain. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 May 1;64(Pt, 5):409-12. Epub 2008 Apr 24. PMID:18453713 doi:http://dx.doi.org/10.1107/S1744309108009524
Categories: Homo sapiens | Radzimanowski, J. | Sinning, I. | Wild, K. | Aicd | Alzheimer disease | Alzheimer's disease | Amyloid | Apoptosis | App | Cell adhesion | Coated pit | Disease mutation | Endocytosis | Fe65 | Glycoprotein | Heparin-binding | Iron | Membrane | Metal-binding | Notch signaling pathway | Phosphoprotein | Protease inhibitor | Protein binding | Proteoglycan | Ptb domain | Serine protease inhibitor | Transmembrane
