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1z76

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[[Image:1z76.png|left|200px]]
[[Image:1z76.png|left|200px]]
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{{STRUCTURE_1z76| PDB=1z76 | SCENE= }}
{{STRUCTURE_1z76| PDB=1z76 | SCENE= }}
===Crystal structure of an acidic phospholipase A2 (BthA-I) from Bothrops jararacussu venom complexed with p-bromophenacyl bromide===
===Crystal structure of an acidic phospholipase A2 (BthA-I) from Bothrops jararacussu venom complexed with p-bromophenacyl bromide===
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{{ABSTRACT_PUBMED_16301802}}
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==See Also==
==See Also==
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*[[Phospholipase A2]]
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*[[Phospholipase A2|Phospholipase A2]]
==Reference==
==Reference==
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<ref group="xtra">PMID:16301802</ref><ref group="xtra">PMID:15158738</ref><ref group="xtra">PMID:15351695</ref><references group="xtra"/>
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<ref group="xtra">PMID:016301802</ref><ref group="xtra">PMID:015158738</ref><ref group="xtra">PMID:015351695</ref><references group="xtra"/>
[[Category: Bothrops jararacussu]]
[[Category: Bothrops jararacussu]]
[[Category: Fontes, M R.]]
[[Category: Fontes, M R.]]
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[[Category: Acidic phospholipase a2]]
[[Category: Acidic phospholipase a2]]
[[Category: Bothrops jararacussu venom]]
[[Category: Bothrops jararacussu venom]]
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[[Category: Crystal structure]]
 
[[Category: Dimeric phospholipase a2]]
[[Category: Dimeric phospholipase a2]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
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[[Category: Phospholipase a2 inhibition]]
[[Category: Phospholipase a2 inhibition]]
[[Category: Platelet aggregation and hypotensive effect]]
[[Category: Platelet aggregation and hypotensive effect]]
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[[Category: X-ray crystallography]]
 

Revision as of 11:47, 25 July 2012

Template:STRUCTURE 1z76

Contents

Crystal structure of an acidic phospholipase A2 (BthA-I) from Bothrops jararacussu venom complexed with p-bromophenacyl bromide

Template:ABSTRACT PUBMED 16301802

About this Structure

1z76 is a 2 chain structure of Phospholipase A2 with sequence from Bothrops jararacussu. Full crystallographic information is available from OCA.

See Also

Reference

  • Magro AJ, Takeda AA, Soares AM, Fontes MR. Structure of BthA-I complexed with p-bromophenacyl bromide: possible correlations with lack of pharmacological activity. Acta Crystallogr D Biol Crystallogr. 2005 Dec;61(Pt 12):1670-7. Epub 2005, Nov 19. PMID:16301802 doi:10.1107/S0907444905029598
  • Takeda AA, dos Santos JI, Marcussi S, Silveira LB, Soares AM, Fontes MR. Crystallization and preliminary X-ray diffraction analysis of an acidic phospholipase A(2) complexed with p-bromophenacyl bromide and alpha-tocopherol inhibitors at 1.9- and 1.45-A resolution. Biochim Biophys Acta. 2004 Jun 1;1699(1-2):281-4. PMID:15158738 doi:10.1016/j.bbapap.2004.02.005
  • Magro AJ, Murakami MT, Marcussi S, Soares AM, Arni RK, Fontes MR. Crystal structure of an acidic platelet aggregation inhibitor and hypotensive phospholipase A2 in the monomeric and dimeric states: insights into its oligomeric state. Biochem Biophys Res Commun. 2004 Oct 8;323(1):24-31. PMID:15351695 doi:10.1016/j.bbrc.2004.08.046

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