2jle
From Proteopedia
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[[Image:2jle.png|left|200px]] | [[Image:2jle.png|left|200px]] | ||
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{{STRUCTURE_2jle| PDB=2jle | SCENE= }} | {{STRUCTURE_2jle| PDB=2jle | SCENE= }} | ||
===NOVEL INDAZOLE NNRTIS CREATED USING MOLECULAR TEMPLATE HYBRIDIZATION BASED ON CRYSTALLOGRAPHIC OVERLAYS=== | ===NOVEL INDAZOLE NNRTIS CREATED USING MOLECULAR TEMPLATE HYBRIDIZATION BASED ON CRYSTALLOGRAPHIC OVERLAYS=== | ||
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{{ABSTRACT_PUBMED_19175319}} | {{ABSTRACT_PUBMED_19175319}} | ||
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==See Also== | ==See Also== | ||
| - | *[[Reverse transcriptase]] | + | *[[Reverse transcriptase|Reverse transcriptase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019175319</ref><references group="xtra"/> |
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Allan, G.]] | [[Category: Allan, G.]] | ||
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[[Category: Capsid maturation]] | [[Category: Capsid maturation]] | ||
[[Category: Capsid protein]] | [[Category: Capsid protein]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Dna integration]] | [[Category: Dna integration]] | ||
[[Category: Dna recombination]] | [[Category: Dna recombination]] | ||
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[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
| - | [[Category: Ribosomal frameshifting]] | ||
[[Category: Rna-binding]] | [[Category: Rna-binding]] | ||
[[Category: Rna-directed dna polymerase]] | [[Category: Rna-directed dna polymerase]] | ||
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[[Category: Viral nucleoprotein]] | [[Category: Viral nucleoprotein]] | ||
[[Category: Virion]] | [[Category: Virion]] | ||
| - | [[Category: Zinc]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
Revision as of 11:57, 25 July 2012
Contents |
NOVEL INDAZOLE NNRTIS CREATED USING MOLECULAR TEMPLATE HYBRIDIZATION BASED ON CRYSTALLOGRAPHIC OVERLAYS
Template:ABSTRACT PUBMED 19175319
About this Structure
2jle is a 2 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Jones LH, Allan G, Barba O, Burt C, Corbau R, Dupont T, Knochel T, Irving S, Middleton DS, Mowbray CE, Perros M, Ringrose H, Swain NA, Webster R, Westby M, Phillips C. Novel indazole non-nucleoside reverse transcriptase inhibitors using molecular hybridization based on crystallographic overlays. J Med Chem. 2009 Feb 26;52(4):1219-23. PMID:19175319 doi:10.1021/jm801322h
Categories: Human immunodeficiency virus 1 | Allan, G. | Barba, O. | Burt, C. | Corbau, R. | Dupont, T. | Irving, S. | Jones, L H. | Mowbray, C E. | Phillips, C. | Swain, N A. | Webster, R. | Westby, M. | Aid | Aspartyl protease | Capsid maturation | Capsid protein | Dna integration | Dna recombination | Dna-directed dna polymerase | Endonuclease | Hiv-1 | Hydrolase | Lipoprotein | Magnesium | Metal-binding | Multifunctional enzyme | Myristate | Nnrti | Nuclease | Nucleotidyltransferase | Nucleus | Phosphoprotein | Protease | Rna-binding | Rna-directed dna polymerase | Transferase | Viral nucleoprotein | Virion | Zinc-finger
