3o5x

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{{STRUCTURE_3o5x| PDB=3o5x | SCENE= }}
{{STRUCTURE_3o5x| PDB=3o5x | SCENE= }}
===Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor===
===Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor===
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{{ABSTRACT_PUBMED_20170098}}
{{ABSTRACT_PUBMED_20170098}}
==About this Structure==
==About this Structure==
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3O5X is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3jrl 3jrl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O5X OCA].
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[[3o5x]] is a 1 chain structure of [[Proten tyrosine phosphatase]] and [[Tyrosine phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3jrl 3jrl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O5X OCA].
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==See Also==
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*[[Proten tyrosine phosphatase|Proten tyrosine phosphatase]]
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*[[Tyrosine phosphatase|Tyrosine phosphatase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20170098</ref><references group="xtra"/>
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<ref group="xtra">PMID:020170098</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Protein-tyrosine-phosphatase]]
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[[Category: Receptor]]
[[Category: Receptor]]
[[Category: Shp2-iib-08 complex]]
[[Category: Shp2-iib-08 complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 15 10:17:37 2010''
 

Revision as of 12:00, 25 July 2012

Image:3o5x.png

Template:STRUCTURE 3o5x

Contents

Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor

Template:ABSTRACT PUBMED 20170098

About this Structure

3o5x is a 1 chain structure of Proten tyrosine phosphatase and Tyrosine phosphatase with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3jrl. Full crystallographic information is available from OCA.

See Also

Reference

  • Zhang X, He Y, Liu S, Yu Z, Jiang ZX, Yang Z, Dong Y, Nabinger SC, Wu L, Gunawan AM, Wang L, Chan RJ, Zhang ZY. Salicylic Acid Based Small Molecule Inhibitor for the Oncogenic Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2). J Med Chem. 2010 Feb 19. PMID:20170098 doi:10.1021/jm901645u

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