2hx3
From Proteopedia
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[[Image:2hx3.png|left|200px]] | [[Image:2hx3.png|left|200px]] | ||
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{{STRUCTURE_2hx3| PDB=2hx3 | SCENE= }} | {{STRUCTURE_2hx3| PDB=2hx3 | SCENE= }} | ||
===Rat nNOS heme domain complexed with (4S)-N-{4-Amino-5-[(2-aminoethyl)-hydroxyamino]-pentyl}-N'-nitroguanidine=== | ===Rat nNOS heme domain complexed with (4S)-N-{4-Amino-5-[(2-aminoethyl)-hydroxyamino]-pentyl}-N'-nitroguanidine=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Nitric Oxide Synthase]] | + | *[[Nitric Oxide Synthase|Nitric Oxide Synthase]] |
==Reference== | ==Reference== | ||
Revision as of 12:00, 25 July 2012
Contents |
Rat nNOS heme domain complexed with (4S)-N-{4-Amino-5-[(2-aminoethyl)-hydroxyamino]-pentyl}-N'-nitroguanidine
Template:ABSTRACT PUBMED 17425297
About this Structure
2hx3 is a 2 chain structure of Nitric Oxide Synthase with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
See Also
Reference
- Seo J, Igarashi J, Li H, Martasek P, Roman LJ, Poulos TL, Silverman RB. Structure-based design and synthesis of N(omega)-nitro-L-arginine-containing peptidomimetics as selective inhibitors of neuronal nitric oxide synthase. Displacement of the heme structural water. J Med Chem. 2007 May 3;50(9):2089-99. Epub 2007 Apr 11. PMID:17425297 doi:10.1021/jm061305c
- Flinspach ML, Li H, Jamal J, Yang W, Huang H, Hah JM, Gomez-Vidal JA, Litzinger EA, Silverman RB, Poulos TL. Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase. Nat Struct Mol Biol. 2004 Jan;11(1):54-9. Epub 2003 Dec 29. PMID:14718923 doi:http://dx.doi.org/10.1038/nsmb704
