2p83

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Revision as of 12:18, 25 July 2012

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Template:STRUCTURE 2p83

Contents 1 Potent and selective isophthalamide S2 hydroxyethylamine inhibitor of BACE1 2 About this Structure 3 See Also 4 Reference

Potent and selective isophthalamide S2 hydroxyethylamine inhibitor of BACE1

Template:ABSTRACT PUBMED 17434734

About this Structure

2p83 is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Beta secretase

Reference

• Kortum SW, Benson TE, Bienkowski MJ, Emmons TL, Prince DB, Paddock DJ, Tomasselli AG, Moon JB, LaBorde A, TenBrink RE. Potent and selective isophthalamide S2 hydroxyethylamine inhibitors of BACE1. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3378-83. Epub 2007 Apr 3. PMID:17434734 doi:10.1016/j.bmcl.2007.03.096