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3kle
From Proteopedia
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[[Image:3kle.png|left|200px]] | [[Image:3kle.png|left|200px]] | ||
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{{STRUCTURE_3kle| PDB=3kle | SCENE= }} | {{STRUCTURE_3kle| PDB=3kle | SCENE= }} | ||
===Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA=== | ===Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA=== | ||
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| - | (as it appears on PubMed at http://www.pubmed.gov), where 20852643 is the PubMed ID number. | ||
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{{ABSTRACT_PUBMED_20852643}} | {{ABSTRACT_PUBMED_20852643}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3kle]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLE OCA]. | + | [[3kle]] is a 16 chain structure of [[AZT-resistant HIV-1 reverse transcriptase]] and [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLE OCA]. |
==See Also== | ==See Also== | ||
| - | *[[AZT-resistant HIV-1 reverse transcriptase]] | + | *[[AZT-resistant HIV-1 reverse transcriptase|AZT-resistant HIV-1 reverse transcriptase]] |
| - | *[[Phl p 2]] | + | *[[Phl p 2|Phl p 2]] |
| + | *[[Reverse transcriptase|Reverse transcriptase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020852643</ref><references group="xtra"/> |
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Arnold, E.]] | [[Category: Arnold, E.]] | ||
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[[Category: Sarafianos, S G.]] | [[Category: Sarafianos, S G.]] | ||
[[Category: Tu, X.]] | [[Category: Tu, X.]] | ||
| + | [[Category: Aid]] | ||
| + | [[Category: Azt]] | ||
| + | [[Category: Azt adenosine dinucleoside tetraphosphate]] | ||
| + | [[Category: Azt resistance mechanism]] | ||
| + | [[Category: Aztp4a]] | ||
| + | [[Category: Aztppppa]] | ||
| + | [[Category: Dna polymerase]] | ||
| + | [[Category: Dna-directed dna polymerase]] | ||
| + | [[Category: Endonuclease]] | ||
| + | [[Category: Hiv]] | ||
| + | [[Category: Hiv-1]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Magnesium]] | ||
| + | [[Category: Metal-binding]] | ||
| + | [[Category: Multifunctional enzyme]] | ||
| + | [[Category: Myristate]] | ||
| + | [[Category: Nrti]] | ||
| + | [[Category: Nrti resistance]] | ||
| + | [[Category: Nuclease]] | ||
| + | [[Category: Nucleoside inhibitor]] | ||
| + | [[Category: Nucleotide excision]] | ||
| + | [[Category: P51/p66]] | ||
| + | [[Category: Resistance mutation]] | ||
| + | [[Category: Reverse transcriptase]] | ||
| + | [[Category: Rna-directed dna polymerase]] | ||
| + | [[Category: Rt]] | ||
| + | [[Category: Thymidine analog mutation]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Transferase-dna complex]] | ||
Revision as of 12:50, 25 July 2012
Contents |
Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA
Template:ABSTRACT PUBMED 20852643
About this Structure
3kle is a 16 chain structure of AZT-resistant HIV-1 reverse transcriptase and Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Tu X, Das K, Han Q, Bauman JD, Clark AD Jr, Hou X, Frenkel YV, Gaffney BL, Jones RA, Boyer PL, Hughes SH, Sarafianos SG, Arnold E. Structural basis of HIV-1 resistance to AZT by excision. Nat Struct Mol Biol. 2010 Oct;17(10):1202-9. Epub 2010 Sep 19. PMID:20852643 doi:10.1038/nsmb.1908
Categories: Human immunodeficiency virus 1 | Arnold, E. | Das, K. | Sarafianos, S G. | Tu, X. | Aid | Azt | Azt adenosine dinucleoside tetraphosphate | Azt resistance mechanism | Aztp4a | Aztppppa | Dna polymerase | Dna-directed dna polymerase | Endonuclease | Hiv | Hiv-1 | Hydrolase | Magnesium | Metal-binding | Multifunctional enzyme | Myristate | Nrti | Nrti resistance | Nuclease | Nucleoside inhibitor | Nucleotide excision | P51/p66 | Resistance mutation | Reverse transcriptase | Rna-directed dna polymerase | Rt | Thymidine analog mutation | Transferase | Transferase-dna complex
