3dpe
From Proteopedia
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[[Image:3dpe.png|left|200px]] | [[Image:3dpe.png|left|200px]] | ||
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{{STRUCTURE_3dpe| PDB=3dpe | SCENE= }} | {{STRUCTURE_3dpe| PDB=3dpe | SCENE= }} | ||
===Crystal structure of the complex between MMP-8 and a non-zinc chelating inhibitor=== | ===Crystal structure of the complex between MMP-8 and a non-zinc chelating inhibitor=== | ||
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{{ABSTRACT_PUBMED_19173605}} | {{ABSTRACT_PUBMED_19173605}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3dpe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DPE OCA]. | + | [[3dpe]] is a 1 chain structure of [[Matrix metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DPE OCA]. |
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| + | ==See Also== | ||
| + | *[[Matrix metalloproteinase|Matrix metalloproteinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019173605</ref><ref group="xtra">PMID:015734640</ref><ref group="xtra">PMID:017623656</ref><ref group="xtra">PMID:015289103</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Neutrophil collagenase]] | [[Category: Neutrophil collagenase]] | ||
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[[Category: Montanari, R.]] | [[Category: Montanari, R.]] | ||
[[Category: Pochetti, G.]] | [[Category: Pochetti, G.]] | ||
| - | [[Category: Calcium]] | ||
[[Category: Collagen degradation]] | [[Category: Collagen degradation]] | ||
[[Category: Extracellular matrix]] | [[Category: Extracellular matrix]] | ||
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[[Category: Metalloprotease]] | [[Category: Metalloprotease]] | ||
[[Category: Non-zinc chelating inhibitor]] | [[Category: Non-zinc chelating inhibitor]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Selective inhibition]] | [[Category: Selective inhibition]] | ||
| - | [[Category: Zinc]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 13:04, 25 July 2012
Contents |
Crystal structure of the complex between MMP-8 and a non-zinc chelating inhibitor
Template:ABSTRACT PUBMED 19173605
About this Structure
3dpe is a 1 chain structure of Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Pochetti G, Montanari R, Gege C, Chevrier C, Taveras AG, Mazza F. Extra Binding Region Induced by Non-Zinc Chelating Inhibitors into the S(1)' Subsite of Matrix Metalloproteinase 8 (MMP-8) (dagger). J Med Chem. 2009 Jan 27. PMID:19173605 doi:http://dx.doi.org/10.1021/jm801166j
- Wasserman ZR. Making a new turn in matrix metalloprotease inhibition. Chem Biol. 2005 Feb;12(2):143-4. PMID:15734640 doi:http://dx.doi.org/10.1016/j.chembiol.2005.01.008
- Johnson AR, Pavlovsky AG, Ortwine DF, Prior F, Man CF, Bornemeier DA, Banotai CA, Mueller WT, McConnell P, Yan C, Baragi V, Lesch C, Roark WH, Wilson M, Datta K, Guzman R, Han HK, Dyer RD. Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects. J Biol Chem. 2007 Sep 21;282(38):27781-91. Epub 2007 Jul 10. PMID:17623656 doi:http://dx.doi.org/10.1074/jbc.M703286200
- Morales R, Perrier S, Florent JM, Beltra J, Dufour S, De Mendez I, Manceau P, Tertre A, Moreau F, Compere D, Dublanchet AC, O'Gara M. Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12. J Mol Biol. 2004 Aug 20;341(4):1063-76. PMID:15289103 doi:http://dx.doi.org/10.1016/j.jmb.2004.06.039
