2vti
From Proteopedia
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===IDENTIFICATION OF N-(4-PIPERIDINYL)-4-(2,6-DICHLOROBENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXAMIDE (AT7519), A NOVEL CYCLIN DEPENDENT KINASE INHIBITOR USING FRAGMENT-BASED X-RAY CRYSTALLOGRAPHY AND STRUCTURE BASED DRUG DESIGN.=== | ===IDENTIFICATION OF N-(4-PIPERIDINYL)-4-(2,6-DICHLOROBENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXAMIDE (AT7519), A NOVEL CYCLIN DEPENDENT KINASE INHIBITOR USING FRAGMENT-BASED X-RAY CRYSTALLOGRAPHY AND STRUCTURE BASED DRUG DESIGN.=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2vti]] is a 1 chain structure of [[Cell Division Protein Kinase 2]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VTI OCA]. | |
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| + | ==See Also== | ||
| + | *[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018656911</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Berdini, V.]] | [[Category: Berdini, V.]] | ||
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[[Category: Serine/threonine protein kinase]] | [[Category: Serine/threonine protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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Revision as of 13:04, 25 July 2012
Contents |
IDENTIFICATION OF N-(4-PIPERIDINYL)-4-(2,6-DICHLOROBENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXAMIDE (AT7519), A NOVEL CYCLIN DEPENDENT KINASE INHIBITOR USING FRAGMENT-BASED X-RAY CRYSTALLOGRAPHY AND STRUCTURE BASED DRUG DESIGN.
Template:ABSTRACT PUBMED 18656911
About this Structure
2vti is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wyatt PG, Woodhead AJ, Berdini V, Boulstridge JA, Carr MG, Cross DM, Davis DJ, Devine LA, Early TR, Feltell RE, Lewis EJ, McMenamin RL, Navarro EF, O'Brien MA, O'Reilly M, Reule M, Saxty G, Seavers LC, Smith DM, Squires MS, Trewartha G, Walker MT, Woolford AJ. Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a novel cyclin dependent kinase inhibitor using fragment-based X-ray crystallography and structure based drug design. J Med Chem. 2008 Aug 28;51(16):4986-99. Epub 2008 Jul 26. PMID:18656911 doi:10.1021/jm800382h
Categories: Homo sapiens | Berdini, V. | Boulstridge, J A. | Brien, M A.O. | Carr, M G. | Cross, D M. | Danillon, D. | Davis, D J. | Devine, L A. | Early, T R. | Feltell, R E. | Lewis, E J. | Mcmenamin, R L. | Navarro, E F. | Reilly, M O. | Reule, M. | Saxty, G. | Seavers, L C.A. | Smith, D. | Squires, M S. | Trewartha, G. | Walker, M T. | Woodhead, A J. | Woolford, A J. | Wyatt, P G. | Cell cycle | Mitosis | Serine/threonine protein kinase | Transferase
