1s63

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Revision as of 13:06, 25 July 2012

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Template:STRUCTURE 1s63

Contents 1 Human protein farnesyltransferase complexed with L-778,123 and FPP 2 About this Structure 3 See Also 4 Reference

Human protein farnesyltransferase complexed with L-778,123 and FPP

Template:ABSTRACT PUBMED 15248757

About this Structure

1s63 is a 2 chain structure of Farnesyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Farnesyltransferase

Reference

• Reid TS, Long SB, Beese LS. Crystallographic analysis reveals that anticancer clinical candidate L-778,123 inhibits protein farnesyltransferase and geranylgeranyltransferase-I by different binding modes. Biochemistry. 2004 Jul 20;43(28):9000-8. PMID:15248757 doi:10.1021/bi049280b