1auy
From Proteopedia
(New page: 200px<br /><applet load="1auy" size="450" color="white" frame="true" align="right" spinBox="true" caption="1auy, resolution 3.00Å" /> '''TURNIP YELLOW MOSAIC...) |
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- | [[Image:1auy.gif|left|200px]]<br /><applet load="1auy" size=" | + | [[Image:1auy.gif|left|200px]]<br /><applet load="1auy" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1auy, resolution 3.00Å" /> | caption="1auy, resolution 3.00Å" /> | ||
'''TURNIP YELLOW MOSAIC VIRUS'''<br /> | '''TURNIP YELLOW MOSAIC VIRUS'''<br /> | ||
==Overview== | ==Overview== | ||
- | The structure of turnip yellow mosaic virus (TYMV) has been solved to 3.2 | + | The structure of turnip yellow mosaic virus (TYMV) has been solved to 3.2 A resolution and an R-value of 18.7%. The structure is consistent with models based on low resolution X-ray and electron microscopy studies, with pentameric and hexameric protein aggregates protruding from the surface and forming deep valleys at the quasi three-fold axes. The N-terminal 26 residues of the A-subunit are disordered, while those of the B- and C-subunits are seen to interact around the interior of the quasi six-fold cluster where they form an annulus. The three histidine residues of each protein subunit are located in the interior and accessible for interaction with the RNA genome. The appearance of the interior surface of the virus capsid, along with buried surface area calculations, suggest that a pentameric unit is lost during decapsidation. |
==About this Structure== | ==About this Structure== | ||
- | 1AUY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Turnip_yellow_mosaic_virus Turnip yellow mosaic virus]. Full crystallographic information is available from [http:// | + | 1AUY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Turnip_yellow_mosaic_virus Turnip yellow mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AUY OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Turnip yellow mosaic virus]] | [[Category: Turnip yellow mosaic virus]] | ||
- | [[Category: Canady, M | + | [[Category: Canady, M A.]] |
[[Category: Day, J.]] | [[Category: Day, J.]] | ||
- | [[Category: Larson, S | + | [[Category: Larson, S B.]] |
[[Category: McPherson, A.]] | [[Category: McPherson, A.]] | ||
[[Category: capsid protein]] | [[Category: capsid protein]] | ||
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[[Category: plant virus]] | [[Category: plant virus]] | ||
- | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:48:30 2008'' |
Revision as of 09:48, 21 February 2008
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TURNIP YELLOW MOSAIC VIRUS
Overview
The structure of turnip yellow mosaic virus (TYMV) has been solved to 3.2 A resolution and an R-value of 18.7%. The structure is consistent with models based on low resolution X-ray and electron microscopy studies, with pentameric and hexameric protein aggregates protruding from the surface and forming deep valleys at the quasi three-fold axes. The N-terminal 26 residues of the A-subunit are disordered, while those of the B- and C-subunits are seen to interact around the interior of the quasi six-fold cluster where they form an annulus. The three histidine residues of each protein subunit are located in the interior and accessible for interaction with the RNA genome. The appearance of the interior surface of the virus capsid, along with buried surface area calculations, suggest that a pentameric unit is lost during decapsidation.
About this Structure
1AUY is a Single protein structure of sequence from Turnip yellow mosaic virus. Full crystallographic information is available from OCA.
Reference
Crystal structure of turnip yellow mosaic virus., Canady MA, Larson SB, Day J, McPherson A, Nat Struct Biol. 1996 Sep;3(9):771-81. PMID:8784351
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