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2xpk
From Proteopedia
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===CELL-PENETRANT, NANOMOLAR O-GLCNACASE INHIBITORS SELECTIVE AGAINST LYSOSOMAL HEXOSAMINIDASES=== | ===CELL-PENETRANT, NANOMOLAR O-GLCNACASE INHIBITORS SELECTIVE AGAINST LYSOSOMAL HEXOSAMINIDASES=== | ||
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{{ABSTRACT_PUBMED_21095575}} | {{ABSTRACT_PUBMED_21095575}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2xpk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XPK OCA]. | + | [[2xpk]] is a 2 chain structure of [[Beta-Hexosaminidase]] with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XPK OCA]. |
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| + | ==See Also== | ||
| + | *[[Beta-Hexosaminidase|Beta-Hexosaminidase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021095575</ref><references group="xtra"/> |
[[Category: Beta-N-acetylhexosaminidase]] | [[Category: Beta-N-acetylhexosaminidase]] | ||
[[Category: Clostridium perfringens]] | [[Category: Clostridium perfringens]] | ||
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[[Category: Schimpl, M.]] | [[Category: Schimpl, M.]] | ||
[[Category: Zheng, X.]] | [[Category: Zheng, X.]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Signalling]] | ||
Revision as of 13:26, 25 July 2012
Contents |
CELL-PENETRANT, NANOMOLAR O-GLCNACASE INHIBITORS SELECTIVE AGAINST LYSOSOMAL HEXOSAMINIDASES
Template:ABSTRACT PUBMED 21095575
About this Structure
2xpk is a 2 chain structure of Beta-Hexosaminidase with sequence from Clostridium perfringens. Full crystallographic information is available from OCA.
See Also
Reference
- Dorfmueller HC, Borodkin VS, Schimpl M, Zheng X, Kime R, Read KD, van Aalten DM. Cell-penetrant, nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases. Chem Biol. 2010 Nov 24;17(11):1250-5. PMID:21095575 doi:10.1016/j.chembiol.2010.09.014
