3oaw

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[[Image:3oaw.png|left|200px]]
[[Image:3oaw.png|left|200px]]
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{{STRUCTURE_3oaw| PDB=3oaw | SCENE= }}
{{STRUCTURE_3oaw| PDB=3oaw | SCENE= }}
===4-Methylpteridineones as Orally Active and Selective PI3K/mTOR Dual Inhibitors===
===4-Methylpteridineones as Orally Active and Selective PI3K/mTOR Dual Inhibitors===
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{{ABSTRACT_PUBMED_20817449}}
{{ABSTRACT_PUBMED_20817449}}
==About this Structure==
==About this Structure==
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3OAW is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OAW OCA].
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[[3oaw]] is a 1 chain structure of [[Phosphoinositide 3-Kinases]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OAW OCA].
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==See Also==
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*[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20817449</ref><references group="xtra"/>
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<ref group="xtra">PMID:020817449</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
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[[Category: Transferase-transferase]]
[[Category: Transferase-transferase]]
[[Category: Transferase-transferase inhibitor complex]]
[[Category: Transferase-transferase inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 6 05:33:47 2010''
 

Revision as of 13:56, 25 July 2012

Template:STRUCTURE 3oaw

Contents

4-Methylpteridineones as Orally Active and Selective PI3K/mTOR Dual Inhibitors

Template:ABSTRACT PUBMED 20817449

About this Structure

3oaw is a 1 chain structure of Phosphoinositide 3-Kinases with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Liu KK, Bagrodia S, Bailey S, Cheng H, Chen H, Gao L, Greasley S, Hoffman JE, Hu Q, Johnson TO, Knighton D, Liu Z, Marx MA, Nambu MD, Ninkovic S, Pascual B, Rafidi K, Rodgers CM, Smith GL, Sun S, Wang H, Yang A, Yuan J, Zou A. 4-Methylpteridinones as orally active and selective PI3K/mTOR dual inhibitors. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6096-9. Epub 2010 Aug 14. PMID:20817449 doi:10.1016/j.bmcl.2010.08.045

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