2hz4
From Proteopedia
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{{STRUCTURE_2hz4| PDB=2hz4 | SCENE= }} | {{STRUCTURE_2hz4| PDB=2hz4 | SCENE= }} | ||
===Abl kinase domain unligated and in complex with tetrahydrostaurosporine=== | ===Abl kinase domain unligated and in complex with tetrahydrostaurosporine=== | ||
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{{ABSTRACT_PUBMED_17164530}} | {{ABSTRACT_PUBMED_17164530}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Leukemia, Philadelphia chromosome-positive, resistant to imatinib OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=189980 189980]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2hz4]] is a 3 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HZ4 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017164530</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
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[[Category: Liebetanz, J.]] | [[Category: Liebetanz, J.]] | ||
[[Category: Manley, P.]] | [[Category: Manley, P.]] | ||
| + | [[Category: Transferase]] | ||
[[Category: Tyrosine kinase]] | [[Category: Tyrosine kinase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:03:29 2009'' | ||
Revision as of 14:11, 25 July 2012
Contents |
Abl kinase domain unligated and in complex with tetrahydrostaurosporine
Template:ABSTRACT PUBMED 17164530
About this Structure
2hz4 is a 3 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Cowan-Jacob SW, Fendrich G, Floersheimer A, Furet P, Liebetanz J, Rummel G, Rheinberger P, Centeleghe M, Fabbro D, Manley PW. Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia. Acta Crystallogr D Biol Crystallogr. 2007 Jan;63(Pt 1):80-93. Epub 2006, Dec 13. PMID:17164530 doi:http://dx.doi.org/10.1107/S0907444906047287
