1od8
From Proteopedia
(New page: 200px<br /> <applet load="1od8" size="450" color="white" frame="true" align="right" spinBox="true" caption="1od8, resolution 1.05Å" /> '''XYLANASE XYN10A FRO...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1OD8 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]] with XYP, NA, XDL and IMD as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1OD8 OCA]]. | + | 1OD8 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]] with XYP, NA, XDL and IMD as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1OD8 OCA]]. |
==Reference== | ==Reference== | ||
A xylobiose-derived isofagomine lactam glycosidase inhibitor binds as its amide tautomer., Gloster T, Williams SJ, Tarling CA, Roberts S, Dupont C, Jodoin P, Shareck F, Withers SG, Davies GJ, Chem Commun (Camb). 2003 Apr 21;(8):944-5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12744311 12744311] | A xylobiose-derived isofagomine lactam glycosidase inhibitor binds as its amide tautomer., Gloster T, Williams SJ, Tarling CA, Roberts S, Dupont C, Jodoin P, Shareck F, Withers SG, Davies GJ, Chem Commun (Camb). 2003 Apr 21;(8):944-5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12744311 12744311] | ||
| + | [[Category: Endo-1,4-beta-xylanase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Streptomyces lividans]] | [[Category: Streptomyces lividans]] | ||
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[[Category: xylanase]] | [[Category: xylanase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:36:25 2007'' |
Revision as of 11:31, 30 October 2007
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XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-ISOFAGOMINE LACTAM
Overview
The atomic-resolution structure of a xylobiose-derived isofagomine lactam, in complex with the xylanase Xyn10A from Streptomyces lividans reveals, that the lactam is bound to the enzyme as the amide tautomer, with, "reversed" protonation-states for nucleophile and acid-base.
About this Structure
1OD8 is a [Single protein] structure of sequence from [Streptomyces lividans] with XYP, NA, XDL and IMD as [ligands]. Active as [Endo-1,4-beta-xylanase], with EC number [3.2.1.8]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
A xylobiose-derived isofagomine lactam glycosidase inhibitor binds as its amide tautomer., Gloster T, Williams SJ, Tarling CA, Roberts S, Dupont C, Jodoin P, Shareck F, Withers SG, Davies GJ, Chem Commun (Camb). 2003 Apr 21;(8):944-5. PMID:12744311
Page seeded by OCA on Tue Oct 30 13:36:25 2007
