3cds
From Proteopedia
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[[Image:3cds.png|left|200px]] | [[Image:3cds.png|left|200px]] | ||
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===Crystal structure of the complex between PPAR-gamma and the agonist LT248 (clofibric acid analogue)=== | ===Crystal structure of the complex between PPAR-gamma and the agonist LT248 (clofibric acid analogue)=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Peroxisome Proliferator-Activated Receptors]] | + | *[[Peroxisome Proliferator-Activated Receptors|Peroxisome Proliferator-Activated Receptors]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019053776</ref><ref group="xtra">PMID:011698662</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mazza, F.]] | [[Category: Mazza, F.]] | ||
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[[Category: Pochetti, G.]] | [[Category: Pochetti, G.]] | ||
[[Category: Activator]] | [[Category: Activator]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Bundle of alpha-helices and a small four-stranded beta-sheet]] | [[Category: Bundle of alpha-helices and a small four-stranded beta-sheet]] | ||
[[Category: Diabetes mellitus]] | [[Category: Diabetes mellitus]] | ||
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[[Category: Obesity]] | [[Category: Obesity]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
| - | [[Category: Zinc]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
Revision as of 14:32, 25 July 2012
Contents |
Crystal structure of the complex between PPAR-gamma and the agonist LT248 (clofibric acid analogue)
Template:ABSTRACT PUBMED 19053776
About this Structure
3cds is a 2 chain structure of Peroxisome Proliferator-Activated Receptors with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Montanari R, Saccoccia F, Scotti E, Crestani M, Godio C, Gilardi F, Loiodice F, Fracchiolla G, Laghezza A, Tortorella P, Lavecchia A, Novellino E, Mazza F, Aschi M, Pochetti G. Crystal structure of the peroxisome proliferator-activated receptor gamma (PPARgamma) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic pocket could be exploited for drug design. J Med Chem. 2008 Dec 25;51(24):7768-76. PMID:19053776 doi:10.1021/jm800733h
- Xu HE, Lambert MH, Montana VG, Plunket KD, Moore LB, Collins JL, Oplinger JA, Kliewer SA, Gampe RT Jr, McKee DD, Moore JT, Willson TM. Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13919-24. Epub 2001 Nov 6. PMID:11698662 doi:10.1073/pnas.241410198
Categories: Homo sapiens | Mazza, F. | Montanari, R. | Pochetti, G. | Activator | Bundle of alpha-helices and a small four-stranded beta-sheet | Diabetes mellitus | Disease mutation | Dna-binding | Metal-binding | Nucleus | Obesity | Phosphoprotein | Receptor | Transcription | Transcription regulation | Zinc-finger
