3e8r
From Proteopedia
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{{STRUCTURE_3e8r| PDB=3e8r | SCENE= }} | {{STRUCTURE_3e8r| PDB=3e8r | SCENE= }} | ||
===Crystal structure of catalytic domain of TACE with hydroxamate inhibitor=== | ===Crystal structure of catalytic domain of TACE with hydroxamate inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3e8r]] is a 2 chain structure of [[A Disintegrin And Metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E8R OCA]. | |
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| + | ==See Also== | ||
| + | *[[A Disintegrin And Metalloproteinase|A Disintegrin And Metalloproteinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018835710</ref><references group="xtra"/> |
[[Category: ADAM 17 endopeptidase]] | [[Category: ADAM 17 endopeptidase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Orth, P.]] | [[Category: Orth, P.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
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[[Category: Tace adam17 zn-endopeptidase]] | [[Category: Tace adam17 zn-endopeptidase]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
| - | [[Category: Zinc]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:42:07 2009'' | ||
Revision as of 15:03, 25 July 2012
Contents |
Crystal structure of catalytic domain of TACE with hydroxamate inhibitor
Template:ABSTRACT PUBMED 18835710
About this Structure
3e8r is a 2 chain structure of A Disintegrin And Metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Mazzola RD Jr, Zhu Z, Sinning L, McKittrick B, Lavey B, Spitler J, Kozlowski J, Neng-Yang S, Zhou G, Guo Z, Orth P, Madison V, Sun J, Lundell D, Niu X. Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: optimization of the S3' pocket. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5809-14. Epub 2008 Sep 13. PMID:18835710 doi:10.1016/j.bmcl.2008.09.045
