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2gs0

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[[Image:2gs0.png|left|200px]]
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{{STRUCTURE_2gs0| PDB=2gs0 | SCENE= }}
{{STRUCTURE_2gs0| PDB=2gs0 | SCENE= }}
===NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the activation domain of p53===
===NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the activation domain of p53===
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{{ABSTRACT_PUBMED_16793543}}
{{ABSTRACT_PUBMED_16793543}}
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==Disease==
 
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Known disease associated with this structure: Adrenal cortical carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Breast cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Choroid plexus papilloma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Colorectal cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Hepatocellular carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Li-Fraumeni syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Li-Fraumeni-like syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Nasopharyngeal carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Osteosarcoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Pancreatic cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]]
 
==About this Structure==
==About this Structure==
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2GS0 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GS0 OCA].
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[[2gs0]] is a 2 chain structure of [[P53]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GS0 OCA].
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==See Also==
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*[[P53|P53]]
==Reference==
==Reference==
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<ref group="xtra">PMID:16793543</ref><references group="xtra"/>
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<ref group="xtra">PMID:016793543</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Tfiih]]
[[Category: Tfiih]]
[[Category: Transcription]]
[[Category: Transcription]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:51:10 2009''
 

Revision as of 15:17, 25 July 2012

Image:2gs0.png

Template:STRUCTURE 2gs0

Contents

NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the activation domain of p53

Template:ABSTRACT PUBMED 16793543

About this Structure

2gs0 is a 2 chain structure of P53 with sequence from Homo sapiens and Saccharomyces cerevisiae. Full experimental information is available from OCA.

See Also

Reference

  • Di Lello P, Jenkins LM, Jones TN, Nguyen BD, Hara T, Yamaguchi H, Dikeakos JD, Appella E, Legault P, Omichinski JG. Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53. Mol Cell. 2006 Jun 23;22(6):731-40. PMID:16793543 doi:http://dx.doi.org/10.1016/j.molcel.2006.05.007

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