3pdj
From Proteopedia
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| - | [[Image:3pdj. | + | [[Image:3pdj.png|left|200px]] |
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===Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase 1 (11b-HSD1) in Complex with 4,4-Disubstituted Cyclohexylbenzamide Inhibitor=== | ===Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase 1 (11b-HSD1) in Complex with 4,4-Disubstituted Cyclohexylbenzamide Inhibitor=== | ||
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{{ABSTRACT_PUBMED_21093258}} | {{ABSTRACT_PUBMED_21093258}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3pdj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PDJ OCA]. | + | [[3pdj]] is a 2 chain structure of [[Hydroxysteroid dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PDJ OCA]. |
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| + | ==See Also== | ||
| + | *[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]] | ||
==Reference== | ==Reference== | ||
Revision as of 15:29, 25 July 2012
Contents |
Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase 1 (11b-HSD1) in Complex with 4,4-Disubstituted Cyclohexylbenzamide Inhibitor
Template:ABSTRACT PUBMED 21093258
About this Structure
3pdj is a 2 chain structure of Hydroxysteroid dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Sun D, Wang Z, Caille S, DeGraffenreid M, Gonzalez-Lopez de Turiso F, Hungate R, Jaen JC, Jiang B, Julian LD, Kelly R, McMinn DL, Kaizerman J, Rew Y, Sudom A, Tu H, Ursu S, Walker N, Willcockson M, Yan X, Ye Q, Powers JP. Synthesis and optimization of novel 4,4-disubstituted cyclohexylbenzamide derivatives as potent 11beta-HSD1 inhibitors. Bioorg Med Chem Lett. 2011 Jan 1;21(1):405-10. Epub 2010 Oct 31. PMID:21093258 doi:10.1016/j.bmcl.2010.10.129
