1e1y

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[[Image:1e1y.png|left|200px]]
[[Image:1e1y.png|left|200px]]
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{{STRUCTURE_1e1y| PDB=1e1y | SCENE= }}
{{STRUCTURE_1e1y| PDB=1e1y | SCENE= }}
===FLAVOPIRIDOL INHIBITS GLYCOGEN PHOSPHORYLASE BY BINDING AT THE INHIBITOR SITE===
===FLAVOPIRIDOL INHIBITS GLYCOGEN PHOSPHORYLASE BY BINDING AT THE INHIBITOR SITE===
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==See Also==
==See Also==
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*[[Glycogen Phosphorylase]]
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*[[Glycogen Phosphorylase|Glycogen Phosphorylase]]
==Reference==
==Reference==

Revision as of 15:42, 25 July 2012

Template:STRUCTURE 1e1y

Contents

FLAVOPIRIDOL INHIBITS GLYCOGEN PHOSPHORYLASE BY BINDING AT THE INHIBITOR SITE

Template:ABSTRACT PUBMED 10924512

About this Structure

1e1y is a 1 chain structure of Glycogen Phosphorylase with sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.

See Also

Reference

  • Oikonomakos NG, Schnier JB, Zographos SE, Skamnaki VT, Tsitsanou KE, Johnson LN. Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site. J Biol Chem. 2000 Nov 3;275(44):34566-73. PMID:10924512 doi:http://dx.doi.org/10.1074/jbc.M004485200
  • Oikonomakos NG, Tsitsanou KE, Zographos SE, Skamnaki VT, Goldmann S, Bischoff H. Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbo xylate. Protein Sci. 1999 Oct;8(10):1930-45. PMID:10548038
  • Zographos SE, Oikonomakos NG, Tsitsanou KE, Leonidas DD, Chrysina ED, Skamnaki VT, Bischoff H, Goldmann S, Watson KA, Johnson LN. The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor. Structure. 1997 Nov 15;5(11):1413-25. PMID:9384557

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