3ewj

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Revision as of 16:08, 25 July 2012

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Template:STRUCTURE 3ewj

Contents 1 Crystal structure of catalytic domain of TACE with carboxylate inhibitor 2 About this Structure 3 See Also 4 Reference

Crystal structure of catalytic domain of TACE with carboxylate inhibitor

Template:ABSTRACT PUBMED 19054672

About this Structure

3ewj is a 2 chain structure of A Disintegrin And Metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• A Disintegrin And Metalloproteinase

Reference

• Guo Z, Orth P, Wong SC, Lavey BJ, Shih NY, Niu X, Lundell DJ, Madison V, Kozlowski JA. Discovery of novel spirocyclopropyl hydroxamate and carboxylate compounds as TACE inhibitors. Bioorg Med Chem Lett. 2009 Jan 1;19(1):54-7. Epub 2008 Nov 14. PMID:19054672 doi:10.1016/j.bmcl.2008.11.034