3oya

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[[Image:3oya.png|left|200px]]
[[Image:3oya.png|left|200px]]
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{{STRUCTURE_3oya| PDB=3oya | SCENE= }}
{{STRUCTURE_3oya| PDB=3oya | SCENE= }}
===Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and raltegravir at 2.65 resolution===
===Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and raltegravir at 2.65 resolution===
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{{ABSTRACT_PUBMED_21030679}}
{{ABSTRACT_PUBMED_21030679}}
==About this Structure==
==About this Structure==
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[[3oya]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_spumaretrovirus Human spumaretrovirus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l2t 3l2t]. The March 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Integrase'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_3 10.2210/rcsb_pdb/mom_2011_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OYA OCA].
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[[3oya]] is a 4 chain structure of [[Retroviral Integrase]] with sequence from [http://en.wikipedia.org/wiki/Human_spumaretrovirus Human spumaretrovirus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l2t 3l2t]. The March 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Integrase'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_3 10.2210/rcsb_pdb/mom_2011_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OYA OCA].
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==See Also==
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*[[Retroviral Integrase|Retroviral Integrase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:21030679</ref><references group="xtra"/>
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<ref group="xtra">PMID:021030679</ref><references group="xtra"/>
[[Category: Human spumaretrovirus]]
[[Category: Human spumaretrovirus]]
[[Category: Integrase]]
[[Category: Integrase]]
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[[Category: Cherepanov, P.]]
[[Category: Cherepanov, P.]]
[[Category: Hare, S.]]
[[Category: Hare, S.]]
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[[Category: Dna integration]]
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[[Category: Dna-binding]]
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[[Category: Dna-binding protein-dna complex]]
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[[Category: Endonuclease]]
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[[Category: Hhcc motif]]
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[[Category: Inhibitor]]
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[[Category: Metal-binding]]
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[[Category: Multifunctional enzyme]]
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[[Category: Nuclease]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Nucleus]]
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[[Category: Protein-dna complex]]
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[[Category: Recombination]]
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[[Category: Tetramer]]
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[[Category: Transferase]]
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[[Category: Viral nucleoprotein]]
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[[Category: Viral protein]]
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[[Category: Viral protein-dna complex]]
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[[Category: Virion]]
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[[Category: Zinc binding]]

Revision as of 16:11, 25 July 2012

Template:STRUCTURE 3oya

Contents

Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and raltegravir at 2.65 resolution

Template:ABSTRACT PUBMED 21030679

About this Structure

3oya is a 4 chain structure of Retroviral Integrase with sequence from Human spumaretrovirus. This structure supersedes the now removed PDB entry 3l2t. The March 2011 RCSB PDB Molecule of the Month feature on Integrase by David Goodsell is 10.2210/rcsb_pdb/mom_2011_3. Full crystallographic information is available from OCA.

See Also

Reference

  • Hare S, Vos AM, Clayton RF, Thuring JW, Cummings MD, Cherepanov P. Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance. Proc Natl Acad Sci U S A. 2010 Oct 28. PMID:21030679 doi:10.1073/pnas.1010246107

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