2pgq
From Proteopedia
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[[Image:2pgq.png|left|200px]] | [[Image:2pgq.png|left|200px]] | ||
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{{STRUCTURE_2pgq| PDB=2pgq | SCENE= }} | {{STRUCTURE_2pgq| PDB=2pgq | SCENE= }} | ||
===Human thrombin mutant C191A-C220A in complex with the inhibitor PPACK=== | ===Human thrombin mutant C191A-C220A in complex with the inhibitor PPACK=== | ||
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| - | The line below this paragraph, {{ABSTRACT_PUBMED_17636263}}, adds the Publication Abstract to the page | ||
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{{ABSTRACT_PUBMED_17636263}} | {{ABSTRACT_PUBMED_17636263}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2pgq]] is a | + | [[2pgq]] is a 2 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PGQ OCA]. |
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| + | ==See Also== | ||
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017636263</ref><ref group="xtra">PMID:015152000</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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[[Category: Mathews, F S.]] | [[Category: Mathews, F S.]] | ||
[[Category: Pineda, A O.]] | [[Category: Pineda, A O.]] | ||
| - | [[Category: Hydrolase]] | + | [[Category: Hydrolase-hydrolase inhibitor complex]] |
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
Revision as of 16:12, 25 July 2012
Contents |
Human thrombin mutant C191A-C220A in complex with the inhibitor PPACK
Template:ABSTRACT PUBMED 17636263
About this Structure
2pgq is a 2 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Bush-Pelc LA, Marino F, Chen Z, Pineda AO, Mathews FS, Di Cera E. Important role of the cys-191 cys-220 disulfide bond in thrombin function and allostery. J Biol Chem. 2007 Sep 14;282(37):27165-70. Epub 2007 Jul 18. PMID:17636263 doi:10.1074/jbc.M703202200
- Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E. Molecular dissection of Na+ binding to thrombin. J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:15152000 doi:http://dx.doi.org/10.1074/jbc.M401756200
