1nt1

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[[Image:1nt1.png|left|200px]]
[[Image:1nt1.png|left|200px]]
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{{STRUCTURE_1nt1| PDB=1nt1 | SCENE= }}
{{STRUCTURE_1nt1| PDB=1nt1 | SCENE= }}
===thrombin in complex with selective macrocyclic inhibitor===
===thrombin in complex with selective macrocyclic inhibitor===
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{{ABSTRACT_PUBMED_12873514}}
{{ABSTRACT_PUBMED_12873514}}
==About this Structure==
==About this Structure==
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[[1nt1]] is a 2 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NT1 OCA].
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[[1nt1]] is a 2 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NT1 OCA].
==See Also==
==See Also==
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*[[Hirudin]]
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*[[Hirudin|Hirudin]]
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*[[Thrombin|Thrombin]]
==Reference==
==Reference==
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<ref group="xtra">PMID:12873514</ref><references group="xtra"/>
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<ref group="xtra">PMID:012873514</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Yan, Y.]]
[[Category: Yan, Y.]]
[[Category: Young, M.]]
[[Category: Young, M.]]
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[[Category: Blood clotting/hydrolase inhibitor complex]]
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[[Category: Blood clotting-hydrolase inhibitor complex]]
[[Category: Thrombin inhibitor complex]]
[[Category: Thrombin inhibitor complex]]

Revision as of 16:51, 25 July 2012

Template:STRUCTURE 1nt1

Contents

thrombin in complex with selective macrocyclic inhibitor

Template:ABSTRACT PUBMED 12873514

About this Structure

1nt1 is a 2 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Nantermet PG, Barrow JC, Newton CL, Pellicore JM, Young M, Lewis SD, Lucas BJ, Krueger JA, McMasters DR, Yan Y, Kuo LC, Vacca JP, Selnick HG. Design and synthesis of potent and selective macrocyclic thrombin inhibitors. Bioorg Med Chem Lett. 2003 Aug 18;13(16):2781-4. PMID:12873514

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