2itq
From Proteopedia
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[[Image:2itq.png|left|200px]] | [[Image:2itq.png|left|200px]] | ||
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{{STRUCTURE_2itq| PDB=2itq | SCENE= }} | {{STRUCTURE_2itq| PDB=2itq | SCENE= }} | ||
===CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN G719S MUTATION IN COMPLEX WITH AFN941=== | ===CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN G719S MUTATION IN COMPLEX WITH AFN941=== | ||
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{{ABSTRACT_PUBMED_17349580}} | {{ABSTRACT_PUBMED_17349580}} | ||
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==See Also== | ==See Also== | ||
| - | *[[Epidermal Growth Factor Receptor]] | + | *[[Epidermal Growth Factor Receptor|Epidermal Growth Factor Receptor]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017349580</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
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[[Category: Yun, C H.]] | [[Category: Yun, C H.]] | ||
[[Category: Afn941]] | [[Category: Afn941]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Anti-oncogene]] | [[Category: Anti-oncogene]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
[[Category: Staurosporine]] | [[Category: Staurosporine]] | ||
Revision as of 17:07, 25 July 2012
Contents |
CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN G719S MUTATION IN COMPLEX WITH AFN941
Template:ABSTRACT PUBMED 17349580
About this Structure
2itq is a 1 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yun CH, Boggon TJ, Li Y, Woo MS, Greulich H, Meyerson M, Eck MJ. Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. Cancer Cell. 2007 Mar;11(3):217-27. PMID:17349580 doi:http://dx.doi.org/10.1016/j.ccr.2006.12.017
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Boggon, T J. | Eck, M J. | Greulich, H. | Li, Y. | Meyerson, M. | Woo, S. | Yun, C H. | Afn941 | Anti-oncogene | Atp-binding | Cell cycle | Disease mutation | Egfr | Epidermal growth factor | G719 | Glycoprotein | Membrane | Nucleotide-binding | Phosphorylation | Receptor | Staurosporine | Transferase | Transmembrane | Tyrosine-protein kinase
