3t9t
From Proteopedia
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[[Image:3t9t.png|left|200px]] | [[Image:3t9t.png|left|200px]] | ||
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{{STRUCTURE_3t9t| PDB=3t9t | SCENE= }} | {{STRUCTURE_3t9t| PDB=3t9t | SCENE= }} | ||
===Crystal structure of BTK mutant (F435T,K596R) complexed with Imidazo[1,5-a]quinoxaline=== | ===Crystal structure of BTK mutant (F435T,K596R) complexed with Imidazo[1,5-a]quinoxaline=== | ||
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{{ABSTRACT_PUBMED_21958547}} | {{ABSTRACT_PUBMED_21958547}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3t9t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T9T OCA]. | + | [[3t9t]] is a 1 chain structure of [[Tyrosine kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T9T OCA]. |
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| + | ==See Also== | ||
| + | *[[Tyrosine kinase|Tyrosine kinase]] | ||
==Reference== | ==Reference== | ||
Revision as of 17:13, 25 July 2012
Contents |
Crystal structure of BTK mutant (F435T,K596R) complexed with Imidazo[1,5-a]quinoxaline
Template:ABSTRACT PUBMED 21958547
About this Structure
3t9t is a 1 chain structure of Tyrosine kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Kim KH, Maderna A, Schnute ME, Hegen M, Mohan S, Miyashiro J, Lin L, Li E, Keegan S, Lussier J, Wrocklage C, Nickerson-Nutter CL, Wittwer AJ, Soutter H, Caspers N, Han S, Kurumbail R, Dunussi-Joannopoulos K, Douhan J 3rd, Wissner A. Imidazo[1,5-a]quinoxalines as irreversible BTK inhibitors for the treatment of rheumatoid arthritis. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6258-63. Epub 2011 Sep 10. PMID:21958547 doi:10.1016/j.bmcl.2011.09.008
