2vh0

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[[Image:2vh0.png|left|200px]]
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{{STRUCTURE_2vh0| PDB=2vh0 | SCENE= }}
{{STRUCTURE_2vh0| PDB=2vh0 | SCENE= }}
===STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: BIARYL PYRROLIDIN-2-ONES INCORPORATING BASIC HETEROCYCLIC MOTIFS===
===STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: BIARYL PYRROLIDIN-2-ONES INCORPORATING BASIC HETEROCYCLIC MOTIFS===
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{{ABSTRACT_PUBMED_18053714}}
{{ABSTRACT_PUBMED_18053714}}
==About this Structure==
==About this Structure==
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2VH0 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VH0 OCA].
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[[2vh0]] is a 2 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VH0 OCA].
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==See Also==
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*[[Factor Xa|Factor Xa]]
==Reference==
==Reference==
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Structure and property based design of factor Xa inhibitors: biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs., Young RJ, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chan C, Charbaut M, Convery MA, Diallo H, Hortense E, Irving WR, Kelly HA, King NP, Kleanthous S, Mason AM, Pateman AJ, Patikis AN, Pinto IL, Pollard DR, Senger S, Shah GP, Toomey JR, Watson NS, Weston HE, Zhou P, Bioorg Med Chem Lett. 2008 Jan 1;18(1):28-33. Epub 2007 Nov 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18053714 18053714]
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<ref group="xtra">PMID:018053714</ref><references group="xtra"/>
[[Category: Coagulation factor Xa]]
[[Category: Coagulation factor Xa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Zhou, P.]]
[[Category: Zhou, P.]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
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[[Category: Calcium]]
 
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Complex]]
[[Category: Complex]]
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Hydroxylation]]
[[Category: Hydroxylation]]
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[[Category: Polymorphism]]
 
[[Category: Protease]]
[[Category: Protease]]
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Zymogen]]
[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Dec 5 09:53:36 2008''
 

Revision as of 17:16, 25 July 2012

Template:STRUCTURE 2vh0

Contents

STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: BIARYL PYRROLIDIN-2-ONES INCORPORATING BASIC HETEROCYCLIC MOTIFS

Template:ABSTRACT PUBMED 18053714

About this Structure

2vh0 is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Young RJ, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chan C, Charbaut M, Convery MA, Diallo H, Hortense E, Irving WR, Kelly HA, King NP, Kleanthous S, Mason AM, Pateman AJ, Patikis AN, Pinto IL, Pollard DR, Senger S, Shah GP, Toomey JR, Watson NS, Weston HE, Zhou P. Structure and property based design of factor Xa inhibitors: biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs. Bioorg Med Chem Lett. 2008 Jan 1;18(1):28-33. Epub 2007 Nov 13. PMID:18053714 doi:S0960-894X(07)01328-5

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