3cj2

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{{STRUCTURE_3cj2| PDB=3cj2 | SCENE= }}
{{STRUCTURE_3cj2| PDB=3cj2 | SCENE= }}
===Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments===
===Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments===
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{{ABSTRACT_PUBMED_18400495}}
{{ABSTRACT_PUBMED_18400495}}
==About this Structure==
==About this Structure==
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3CJ2 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CJ2 OCA].
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[[3cj2]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CJ2 OCA].
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==See Also==
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*[[RNA polymerase|RNA polymerase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:18400495</ref><references group="xtra"/>
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<ref group="xtra">PMID:018400495</ref><references group="xtra"/>
[[Category: Hepatitis c virus subtype 1b]]
[[Category: Hepatitis c virus subtype 1b]]
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
[[Category: Kissinger, c.]]
[[Category: Kissinger, c.]]
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[[Category: Acetylation]]
 
[[Category: Apoptosis]]
[[Category: Apoptosis]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Capsid protein]]
[[Category: Capsid protein]]
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[[Category: Cytoplasm]]
 
[[Category: Drug discovery]]
[[Category: Drug discovery]]
[[Category: Endoplasmic reticulum]]
[[Category: Endoplasmic reticulum]]
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[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
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[[Category: Ubl conjugation]]
 
[[Category: Viral nucleoprotein]]
[[Category: Viral nucleoprotein]]
[[Category: Virion]]
[[Category: Virion]]
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[[Category: Zinc]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:34:51 2009''
 

Revision as of 17:47, 25 July 2012

Image:3cj2.png

Template:STRUCTURE 3cj2

Contents

Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments

Template:ABSTRACT PUBMED 18400495

About this Structure

3cj2 is a 2 chain structure of RNA polymerase with sequence from Hepatitis c virus subtype 1b. Full crystallographic information is available from OCA.

See Also

Reference

  • Antonysamy SS, Aubol B, Blaney J, Browner MF, Giannetti AM, Harris SF, Hebert N, Hendle J, Hopkins S, Jefferson E, Kissinger C, Leveque V, Marciano D, McGee E, Najera I, Nolan B, Tomimoto M, Torres E, Wright T. Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg Med Chem Lett. 2008 May 1;18(9):2990-5. Epub 2008 Mar 22. PMID:18400495 doi:http://dx.doi.org/10.1016/j.bmcl.2008.03.056

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OCA

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