1ycq
From Proteopedia
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===XENOPUS LAEVIS MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF HUMAN P53=== | ===XENOPUS LAEVIS MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF HUMAN P53=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1ycq]] is a 2 chain structure of [[MDM2]] and [[P53]] with sequence from [http://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. The July 2002 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''p53 Tumor Suppressor'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2002_7 10.2210/rcsb_pdb/mom_2002_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YCQ OCA]. | |
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| + | ==See Also== | ||
| + | *[[MDM2|MDM2]] | ||
| + | *[[P53|P53]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:008875929</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/> |
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Xenopus laevis]] | [[Category: Xenopus laevis]] | ||
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[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
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Revision as of 18:05, 25 July 2012
Contents |
XENOPUS LAEVIS MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF HUMAN P53
Template:ABSTRACT PUBMED 8875929
About this Structure
1ycq is a 2 chain structure of MDM2 and P53 with sequence from Xenopus laevis. The July 2002 RCSB PDB Molecule of the Month feature on p53 Tumor Suppressor by David S. Goodsell is 10.2210/rcsb_pdb/mom_2002_7. Full crystallographic information is available from OCA.
See Also
Reference
- Kussie PH, Gorina S, Marechal V, Elenbaas B, Moreau J, Levine AJ, Pavletich NP. Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science. 1996 Nov 8;274(5289):948-53. PMID:8875929
- Hicks JM, Hsu VL. The extended left-handed helix: a simple nucleic acid-binding motif. Proteins. 2004 May 1;55(2):330-8. PMID:15048824 doi:10.1002/prot.10630
