1ycq

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Revision as of 18:05, 25 July 2012

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Template:STRUCTURE 1ycq

Contents 1 XENOPUS LAEVIS MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF HUMAN P53 2 About this Structure 3 See Also 4 Reference

XENOPUS LAEVIS MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF HUMAN P53

Template:ABSTRACT PUBMED 8875929

About this Structure

1ycq is a 2 chain structure of MDM2 and P53 with sequence from Xenopus laevis. The July 2002 RCSB PDB Molecule of the Month feature on p53 Tumor Suppressor by David S. Goodsell is 10.2210/rcsb_pdb/mom_2002_7. Full crystallographic information is available from OCA.

See Also

• MDM2
• P53

Reference

• Kussie PH, Gorina S, Marechal V, Elenbaas B, Moreau J, Levine AJ, Pavletich NP. Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science. 1996 Nov 8;274(5289):948-53. PMID:8875929
• Hicks JM, Hsu VL. The extended left-handed helix: a simple nucleic acid-binding motif. Proteins. 2004 May 1;55(2):330-8. PMID:15048824 doi:10.1002/prot.10630