1t4e
From Proteopedia
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[[Image:1t4e.png|left|200px]] | [[Image:1t4e.png|left|200px]] | ||
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{{STRUCTURE_1t4e| PDB=1t4e | SCENE= }} | {{STRUCTURE_1t4e| PDB=1t4e | SCENE= }} | ||
===Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor=== | ===Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor=== | ||
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{{ABSTRACT_PUBMED_15715460}} | {{ABSTRACT_PUBMED_15715460}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1t4e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T4E OCA]. | + | [[1t4e]] is a 2 chain structure of [[MDM2]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T4E OCA]. |
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| + | ==See Also== | ||
| + | *[[MDM2|MDM2]] | ||
==Reference== | ==Reference== | ||
Revision as of 18:14, 25 July 2012
Contents |
Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor
Template:ABSTRACT PUBMED 15715460
About this Structure
1t4e is a 2 chain structure of MDM2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Grasberger BL, Lu T, Schubert C, Parks DJ, Carver TE, Koblish HK, Cummings MD, LaFrance LV, Milkiewicz KL, Calvo RR, Maguire D, Lattanze J, Franks CF, Zhao S, Ramachandren K, Bylebyl GR, Zhang M, Manthey CL, Petrella EC, Pantoliano MW, Deckman IC, Spurlino JC, Maroney AC, Tomczuk BE, Molloy CJ, Bone RF. Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells. J Med Chem. 2005 Feb 24;48(4):909-12. PMID:15715460 doi:10.1021/jm049137g
