3n49

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Revision as of 18:15, 25 July 2012

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Template:STRUCTURE 3n49

Contents 1 Human FPPS COMPLEX WITH NOV_292 2 About this Structure 3 See Also 4 Reference

Human FPPS COMPLEX WITH NOV_292

Template:ABSTRACT PUBMED 20711197

About this Structure

3n49 is a 1 chain structure of Farnesyl diphosphate synthase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Farnesyl diphosphate synthase

Reference

• Jahnke W, Rondeau JM, Cotesta S, Marzinzik A, Pelle X, Geiser M, Strauss A, Gotte M, Bitsch F, Hemmig R, Henry C, Lehmann S, Glickman JF, Roddy TP, Stout SJ, Green JR. Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat Chem Biol. 2010 Sep;6(9):660-6. Epub 2010 Aug 15. PMID:20711197 doi:10.1038/nchembio.421