3kry

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[[Image:3kry.png|left|200px]]
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[[Image:3kry.jpg|left|200px]]
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{{STRUCTURE_3kry| PDB=3kry | SCENE= }}
{{STRUCTURE_3kry| PDB=3kry | SCENE= }}
===Crystal structure of MMP-13 in complex with SC-78080===
===Crystal structure of MMP-13 in complex with SC-78080===
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{{ABSTRACT_PUBMED_20726512}}
{{ABSTRACT_PUBMED_20726512}}
==About this Structure==
==About this Structure==
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3KRY is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KRY OCA].
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[[3kry]] is a 4 chain structure of [[Matrix metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KRY OCA].
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==See Also==
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*[[Matrix metalloproteinase|Matrix metalloproteinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20726512</ref><references group="xtra"/>
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<ref group="xtra">PMID:020726512</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Becker, D P.]]
[[Category: Becker, D P.]]
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[[Category: Protease]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Secreted]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 6 06:05:00 2010''
 

Revision as of 18:18, 25 July 2012

Template:STRUCTURE 3kry

Contents

Crystal structure of MMP-13 in complex with SC-78080

Template:ABSTRACT PUBMED 20726512

About this Structure

3kry is a 4 chain structure of Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Becker DP, Barta TE, Bedell LJ, Boehm TL, Bond BR, Carroll J, Carron CP, Decrescenzo GA, Easton AM, Freskos JN, Funckes-Shippy CL, Heron M, Hockerman S, Howard CP, Kiefer JR, Li MH, Mathis KJ, McDonald JJ, Mehta PP, Munie GE, Sunyer T, Swearingen CA, Villamil CI, Welsch D, Williams JM, Yu Y, Yao J. Orally active MMP-1 sparing alpha-tetrahydropyranyl and alpha-piperidinyl sulfone matrix metalloproteinase (MMP) inhibitors with efficacy in cancer, arthritis, and cardiovascular disease. J Med Chem. 2010 Sep 23;53(18):6653-80. PMID:20726512 doi:10.1021/jm100669j

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