3bys

From Proteopedia

Revision as of 18:21, 25 July 2012 (edit) OCA (Talk | contribs) ← Previous diff

Revision as of 18:21, 25 July 2012 (edit) (undo) OCA (Talk | contribs) m (Protected "3bys" [edit=sysop:move=sysop]) Next diff →

---

Revision as of 18:21, 25 July 2012

proteopedia linkproteopedia link

Template:STRUCTURE 3bys

Contents 1 co-crystal structure of Lck and aminopyrimidine amide 10b 2 About this Structure 3 See Also 4 Reference

co-crystal structure of Lck and aminopyrimidine amide 10b

Template:ABSTRACT PUBMED 18321037

About this Structure

3bys is a 1 chain structure of Proto-oncogene tyrosine-protein kinase and Tyrosine kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Proto-oncogene tyrosine-protein kinase
• Tyrosine kinase

Reference

• DiMauro EF, Newcomb J, Nunes JJ, Bemis JE, Boucher C, Chai L, Chaffee SC, Deak HL, Epstein LF, Faust T, Gallant P, Gore A, Gu Y, Henkle B, Hsieh F, Huang X, Kim JL, Lee JH, Martin MW, McGowan DC, Metz D, Mohn D, Morgenstern KA, Oliveira-dos-Santos A, Patel VF, Powers D, Rose PE, Schneider S, Tomlinson SA, Tudor YY, Turci SM, Welcher AA, Zhao H, Zhu L, Zhu X. Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation. J Med Chem. 2008 Mar 27;51(6):1681-94. Epub 2008 Mar 6. PMID:18321037 doi:10.1021/jm7010996