3dox
From Proteopedia
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{{STRUCTURE_3dox| PDB=3dox | SCENE= }} | {{STRUCTURE_3dox| PDB=3dox | SCENE= }} | ||
===X-ray structure of HIV-1 protease in situ product complex=== | ===X-ray structure of HIV-1 protease in situ product complex=== | ||
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{{ABSTRACT_PUBMED_18704947}} | {{ABSTRACT_PUBMED_18704947}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3dox]] is a 3 chain structure of [[User:Wayne Decatur/kink-turn motif]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_hxb2_group_m_subtype_b) Human immunodeficiency virus type 1 (isolate hxb2 group m subtype b)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DOX OCA]. | + | [[3dox]] is a 3 chain structure of [[Kink-turn motif]], [[User:Wayne Decatur/kink-turn motif]] and [[Virus protease]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_hxb2_group_m_subtype_b) Human immunodeficiency virus type 1 (isolate hxb2 group m subtype b)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DOX OCA]. |
==See Also== | ==See Also== | ||
| - | *[[User:Wayne Decatur/kink-turn motif]] | + | *[[Kink-turn motif|Kink-turn motif]] |
| + | *[[User:Wayne Decatur/kink-turn motif|User:Wayne Decatur/kink-turn motif]] | ||
| + | *[[Virus protease|Virus protease]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018704947</ref><ref group="xtra">PMID:011170214</ref><ref group="xtra">PMID:015794743</ref><ref group="xtra">PMID:014993705</ref><ref group="xtra">PMID:017116869</ref><references group="xtra"/> |
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Bihani, S.]] | [[Category: Bihani, S.]] | ||
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[[Category: Capsid protein]] | [[Category: Capsid protein]] | ||
[[Category: Catalysis]] | [[Category: Catalysis]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Dna integration]] | [[Category: Dna integration]] | ||
[[Category: Dna recombination]] | [[Category: Dna recombination]] | ||
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[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Reaction intermediate]] | [[Category: Reaction intermediate]] | ||
| - | [[Category: Ribosomal frameshifting]] | ||
[[Category: Rna-binding]] | [[Category: Rna-binding]] | ||
[[Category: Rna-directed dna polymerase]] | [[Category: Rna-directed dna polymerase]] | ||
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[[Category: Virion]] | [[Category: Virion]] | ||
[[Category: X-ray crystallography]] | [[Category: X-ray crystallography]] | ||
| - | [[Category: Zinc]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
Revision as of 19:07, 25 July 2012
Contents |
X-ray structure of HIV-1 protease in situ product complex
Template:ABSTRACT PUBMED 18704947
About this Structure
3dox is a 3 chain structure of Kink-turn motif, User:Wayne Decatur/kink-turn motif and Virus protease with sequence from Human immunodeficiency virus type 1 (isolate hxb2 group m subtype b). Full crystallographic information is available from OCA.
See Also
Reference
- Bihani S, Das A, Prashar V, Ferrer JL, Hosur MV. X-ray structure of HIV-1 protease in situ product complex. Proteins. 2008 Aug 14. PMID:18704947 doi:10.1002/prot.22174
- Pillai B, Kannan KK, Hosur MV. 1.9 A x-ray study shows closed flap conformation in crystals of tethered HIV-1 PR. Proteins. 2001 Apr 1;43(1):57-64. PMID:11170214
- Kumar M, Prashar V, Mahale S, Hosur MV. Observation of a tetrahedral reaction intermediate in the HIV-1 protease-substrate complex. Biochem J. 2005 Jul 15;389(Pt 2):365-71. PMID:15794743 doi:10.1042/BJ20041804
- Pillai B, Kannan KK, Bhat SV, Hosur MV. Rapid screening for HIV-1 protease inhibitor leads through X-ray diffraction. Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):594-6. Epub 2004, Feb 25. PMID:14993705 doi:10.1107/S0907444903029676
- Das A, Prashar V, Mahale S, Serre L, Ferrer JL, Hosur MV. Crystal structure of HIV-1 protease in situ product complex and observation of a low-barrier hydrogen bond between catalytic aspartates. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18464-9. Epub 2006 Nov 20. PMID:17116869
Categories: HIV-1 retropepsin | Bihani, S. | Das, A. | Ferrer, J L. | Hosur, M V. | Prashar, V. | Aid | Aspartyl protease | Capsid maturation | Capsid protein | Catalysis | Dna integration | Dna recombination | Dna-directed dna polymerase | Endonuclease | Hiv-1 protease | Host-virus interaction | Hydrolase | Inhibitor | Lipoprotein | Magnesium | Metal-binding | Multifunctional enzyme | Myristate | Nuclease | Nucleotidyltransferase | Nucleus | Phosphoprotein | Protease | Reaction intermediate | Rna-binding | Rna-directed dna polymerase | Transferase | Transition state | Viral nucleoprotein | Virion | X-ray crystallography | Zinc-finger
