3hdz
From Proteopedia
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{{STRUCTURE_3hdz| PDB=3hdz | SCENE= }} | {{STRUCTURE_3hdz| PDB=3hdz | SCENE= }} | ||
===Identification, Synthesis, and SAR of Amino Substituted Pyrido[3,2b]pryaziones as Potent and Selective PDE5 Inhibitors=== | ===Identification, Synthesis, and SAR of Amino Substituted Pyrido[3,2b]pryaziones as Potent and Selective PDE5 Inhibitors=== | ||
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{{ABSTRACT_PUBMED_19540112}} | {{ABSTRACT_PUBMED_19540112}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3hdz]] is a 1 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HDZ OCA]. | |
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| + | ==See Also== | ||
| + | *[[Phosphodiesterase|Phosphodiesterase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019540112</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Brown, D G.]] | [[Category: Brown, D G.]] | ||
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[[Category: Jacobsen, E J.]] | [[Category: Jacobsen, E J.]] | ||
[[Category: Walker, J K.]] | [[Category: Walker, J K.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Camp]] | [[Category: Camp]] | ||
[[Category: Cgmp]] | [[Category: Cgmp]] | ||
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[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Polymorphism allosteric enzyme]] | [[Category: Polymorphism allosteric enzyme]] | ||
| - | [[Category: Zinc]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 8 09:28:05 2009'' | ||
Revision as of 19:08, 25 July 2012
Contents |
Identification, Synthesis, and SAR of Amino Substituted Pyrido[3,2b]pryaziones as Potent and Selective PDE5 Inhibitors
Template:ABSTRACT PUBMED 19540112
About this Structure
3hdz is a 1 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Owen DR, Walker JK, Jon Jacobsen E, Freskos JN, Hughes RO, Brown DL, Bell AS, Brown DG, Phillips C, Mischke BV, Molyneaux JM, Fobian YM, Heasley SE, Moon JB, Stallings WC, Joseph Rogier D, Fox DN, Palmer MJ, Ringer T, Rodriquez-Lens M, Cubbage JW, Blevis-Bal RM, Benson AG, Acker BA, Maddux TM, Tollefson MB, Bond BR, Macinnes A, Yu Y. Identification, synthesis and SAR of amino substituted pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4088-91. Epub 2009 Jun 6. PMID:19540112 doi:10.1016/j.bmcl.2009.06.012
