4dl5
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | [[Image:4dl5. | + | [[Image:4dl5.png|left|200px]] |
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_4dl5", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_4dl5| PDB=4dl5 | SCENE= }} | {{STRUCTURE_4dl5| PDB=4dl5 | SCENE= }} | ||
===Human DNA polymerase eta inserting dCMPNPP opposite the 5'G of cisplatin crosslinked Gs (Pt-GG2).=== | ===Human DNA polymerase eta inserting dCMPNPP opposite the 5'G of cisplatin crosslinked Gs (Pt-GG2).=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_22529383}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 22529383 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_22529383}} | {{ABSTRACT_PUBMED_22529383}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[4dl5]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DL5 OCA]. | + | [[4dl5]] is a 3 chain structure of [[DNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DL5 OCA]. |
| + | |||
| + | ==See Also== | ||
| + | *[[DNA polymerase|DNA polymerase]] | ||
==Reference== | ==Reference== | ||
Revision as of 19:15, 25 July 2012
Contents |
Human DNA polymerase eta inserting dCMPNPP opposite the 5'G of cisplatin crosslinked Gs (Pt-GG2).
Template:ABSTRACT PUBMED 22529383
About this Structure
4dl5 is a 3 chain structure of DNA polymerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Zhao Y, Biertumpfel C, Gregory MT, Hua YJ, Hanaoka F, Yang W. Structural basis of human DNA polymerase eta-mediated chemoresistance to cisplatin. Proc Natl Acad Sci U S A. 2012 Apr 23. PMID:22529383 doi:10.1073/pnas.1202681109
Categories: DNA-directed DNA polymerase | Homo sapiens | Biertumpfel, Christian | Gregory, M. | Hanaoka, F. | Hua, Y. | Yang, W. | Zhao, Y. | Chemoresistence | Cisplatin | Dna distorsion | Human dna polymerse eta | Inhibition | Kinetic | Molecular splint | Nucleotidyl transfer reaction | Pcna | Second tls polymerase | Transferase-dna-inhibitor complex | Translesion synthesis
