3f16
From Proteopedia
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===Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor (R)-N-(3-hydroxy-1-nitroso-1-oxopropan-2-yl)-4-methoxybenzenesulfonamide=== | ===Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor (R)-N-(3-hydroxy-1-nitroso-1-oxopropan-2-yl)-4-methoxybenzenesulfonamide=== | ||
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{{ABSTRACT_PUBMED_17269766}} | {{ABSTRACT_PUBMED_17269766}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3f16]] is a 1 chain structure of [[Elastase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F16 OCA]. | + | [[3f16]] is a 1 chain structure of [[Elastase]] and [[Matrix metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F16 OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Elastase]] | + | *[[Elastase|Elastase]] |
| + | *[[Matrix metalloproteinase|Matrix metalloproteinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017269766</ref><ref group="xtra">PMID:012813751</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Macrophage elastase]] | [[Category: Macrophage elastase]] | ||
[[Category: Calderone, V.]] | [[Category: Calderone, V.]] | ||
| - | [[Category: Calcium]] | ||
[[Category: Elastase]] | [[Category: Elastase]] | ||
[[Category: Extracellular matrix]] | [[Category: Extracellular matrix]] | ||
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[[Category: Metalloprotease]] | [[Category: Metalloprotease]] | ||
[[Category: Mmp12]] | [[Category: Mmp12]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
| - | [[Category: Zinc]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 19:18, 25 July 2012
Contents |
Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor (R)-N-(3-hydroxy-1-nitroso-1-oxopropan-2-yl)-4-methoxybenzenesulfonamide
Template:ABSTRACT PUBMED 17269766
About this Structure
3f16 is a 1 chain structure of Elastase and Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Bertini I, Calderone V, Fragai M, Giachetti A, Loconte M, Luchinat C, Maletta M, Nativi C, Yeo KJ. Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases. J Am Chem Soc. 2007 Mar 7;129(9):2466-75. Epub 2007 Feb 2. PMID:17269766 doi:10.1021/ja065156z
- Bertini I, Calderone V, Fragai M, Luchinat C, Mangani S, Terni B. X-ray structures of binary and ternary enzyme-product-inhibitor complexes of matrix metalloproteinases. Angew Chem Int Ed Engl. 2003 Jun 16;42(23):2673-6. PMID:12813751 doi:10.1002/anie.200350957
