3qlf
From Proteopedia
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{{STRUCTURE_3qlf| PDB=3qlf | SCENE= }} | {{STRUCTURE_3qlf| PDB=3qlf | SCENE= }} | ||
===Crystal structure of the L317I mutant of the C-src tyrosine kinase domain complexed with pyrazolopyrimidine 5=== | ===Crystal structure of the L317I mutant of the C-src tyrosine kinase domain complexed with pyrazolopyrimidine 5=== | ||
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{{ABSTRACT_PUBMED_17355866}} | {{ABSTRACT_PUBMED_17355866}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3qlf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QLF OCA]. | + | [[3qlf]] is a 2 chain structure of [[C-Src tyrosine kinase]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QLF OCA]. |
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| + | ==See Also== | ||
| + | *[[C-Src tyrosine kinase|C-Src tyrosine kinase]] | ||
==Reference== | ==Reference== | ||
Revision as of 19:21, 25 July 2012
Contents |
Crystal structure of the L317I mutant of the C-src tyrosine kinase domain complexed with pyrazolopyrimidine 5
Template:ABSTRACT PUBMED 17355866
About this Structure
3qlf is a 2 chain structure of C-Src tyrosine kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.
See Also
Reference
- Seeliger MA, Nagar B, Frank F, Cao X, Henderson MN, Kuriyan J. c-Src binds to the cancer drug imatinib with an inactive Abl/c-Kit conformation and a distributed thermodynamic penalty. Structure. 2007 Mar;15(3):299-311. PMID:17355866 doi:10.1016/j.str.2007.01.015
- Dar AC, Lopez MS, Shokat KM. Small molecule recognition of c-Src via the Imatinib-binding conformation. Chem Biol. 2008 Oct 20;15(10):1015-22. PMID:18940662 doi:10.1016/j.chembiol.2008.09.007
