2fl6
From Proteopedia
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[[Image:2fl6.png|left|200px]] | [[Image:2fl6.png|left|200px]] | ||
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{{STRUCTURE_2fl6| PDB=2fl6 | SCENE= }} | {{STRUCTURE_2fl6| PDB=2fl6 | SCENE= }} | ||
===crystal structure of KSP in complex with inhibitor 6=== | ===crystal structure of KSP in complex with inhibitor 6=== | ||
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==See Also== | ==See Also== | ||
- | *[[Kinesin]] | + | *[[Kinesin|Kinesin]] |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016439123</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Yan, Y.]] | [[Category: Yan, Y.]] |
Revision as of 19:24, 25 July 2012
Contents |
crystal structure of KSP in complex with inhibitor 6
Template:ABSTRACT PUBMED 16439123
About this Structure
2fl6 is a 2 chain structure of Kinesin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Fraley ME, Garbaccio RM, Arrington KL, Hoffman WF, Tasber ES, Coleman PJ, Buser CA, Walsh ES, Hamilton K, Fernandes C, Schaber MD, Lobell RB, Tao W, South VJ, Yan Y, Kuo LC, Prueksaritanont T, Shu C, Torrent M, Heimbrook DC, Kohl NE, Huber HE, Hartman GD. Kinesin spindle protein (KSP) inhibitors. Part 2: the design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1775-9. Epub 2006 Jan 24. PMID:16439123 doi:10.1016/j.bmcl.2006.01.030