2fbr

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Revision as of 19:24, 25 July 2012

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Template:STRUCTURE 2fbr

Contents 1 Human transthyretin (TTR) complexed with bivalant amyloid inhibitor (4 carbon linker) 2 About this Structure 3 See Also 4 Reference

Human transthyretin (TTR) complexed with bivalant amyloid inhibitor (4 carbon linker)

Template:ABSTRACT PUBMED 14583036

About this Structure

2fbr is a 2 chain structure of Transthyretin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Transthyretin

Reference

• Green NS, Palaninathan SK, Sacchettini JC, Kelly JW. Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization. J Am Chem Soc. 2003 Nov 5;125(44):13404-14. PMID:14583036 doi:10.1021/ja030294z
• Choi S, Connelly S, Reixach N, Wilson IA, Kelly JW. Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma. Nat Chem Biol. 2010 Feb;6(2):133-9. PMID:20081815 doi:10.1038/nchembio.281