This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1wbg
From Proteopedia
m (Protected "1wbg" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
[[Image:1wbg.png|left|200px]] | [[Image:1wbg.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_1wbg", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_1wbg| PDB=1wbg | SCENE= }} | {{STRUCTURE_1wbg| PDB=1wbg | SCENE= }} | ||
===ACTIVE SITE THROMBIN INHIBITORS=== | ===ACTIVE SITE THROMBIN INHIBITORS=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_15658854}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 15658854 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_15658854}} | {{ABSTRACT_PUBMED_15658854}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1wbg]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WBG OCA]. | + | [[1wbg]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WBG OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Hirudin]] | + | *[[Hirudin|Hirudin]] |
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015658854</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
| Line 36: | Line 26: | ||
[[Category: Acute phase]] | [[Category: Acute phase]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
| + | [[Category: Blood coagulation-inhibitor]] | ||
[[Category: Calcium-binding]] | [[Category: Calcium-binding]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Gamma-carboxyglutamic acid]] | [[Category: Gamma-carboxyglutamic acid]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
| - | [[Category: Hydrolase | + | [[Category: Hydrolase-hydrolase inhibitor complex]] |
| - | + | ||
[[Category: Kringle]] | [[Category: Kringle]] | ||
[[Category: Polymorphisme]] | [[Category: Polymorphisme]] | ||
Revision as of 19:30, 25 July 2012
Contents |
ACTIVE SITE THROMBIN INHIBITORS
Template:ABSTRACT PUBMED 15658854
About this Structure
1wbg is a 3 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Hartshorn MJ, Murray CW, Cleasby A, Frederickson M, Tickle IJ, Jhoti H. Fragment-based lead discovery using X-ray crystallography. J Med Chem. 2005 Jan 27;48(2):403-13. PMID:15658854 doi:http://dx.doi.org/10.1021/jm0495778
Categories: Homo sapiens | Thrombin | Cleasby, A. | Frederickson, M. | Hartshorn, M J. | Jhoti, H. | Murray, C W. | Tickle, I J. | Acute phase | Blood coagulation | Blood coagulation-inhibitor | Calcium-binding | Disease mutation | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase-hydrolase inhibitor complex | Kringle | Polymorphisme | Serine protease | Sulfation | Vitamin k | Zymogen
