1brz
From Proteopedia
(New page: 200px<br /><applet load="1brz" size="450" color="white" frame="true" align="right" spinBox="true" caption="1brz" /> '''SOLUTION STRUCTURE OF THE SWEET PROTEIN BRAZ...) |
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| - | [[Image:1brz.gif|left|200px]]<br /><applet load="1brz" size=" | + | [[Image:1brz.gif|left|200px]]<br /><applet load="1brz" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1brz" /> | caption="1brz" /> | ||
'''SOLUTION STRUCTURE OF THE SWEET PROTEIN BRAZZEIN, NMR, 43 STRUCTURES'''<br /> | '''SOLUTION STRUCTURE OF THE SWEET PROTEIN BRAZZEIN, NMR, 43 STRUCTURES'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The fruit of Pentadiplandra brazzeana Baillon contains a small, sweet-tasting protein named brazzein. The structure of brazzein in | + | The fruit of Pentadiplandra brazzeana Baillon contains a small, sweet-tasting protein named brazzein. The structure of brazzein in solution was determined by proton nuclear magnetic resonance spectroscopy at pH 5.2 and 22 degrees C. The brazzein fold, which contains one alpha-helix and three strands of antiparallel beta-sheet, does not resemble that of either of the other two sweet-tasting proteins with known structures, monellin and thaumatin. Instead, the structure of brazzein resembles those of plant gamma-thionins and defensins and arthropod toxins. Sequence comparisons predict that members of a newly-identified family of serine proteinase inhibitors share the brazzein fold. |
==About this Structure== | ==About this Structure== | ||
| - | 1BRZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pentadiplandra_brazzeana Pentadiplandra brazzeana]. Full crystallographic information is available from [http:// | + | 1BRZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pentadiplandra_brazzeana Pentadiplandra brazzeana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BRZ OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Abildgaard, F.]] | [[Category: Abildgaard, F.]] | ||
| - | [[Category: Caldwell, J | + | [[Category: Caldwell, J E.]] |
[[Category: Dzakula, Z.]] | [[Category: Dzakula, Z.]] | ||
[[Category: Hellekant, G.]] | [[Category: Hellekant, G.]] | ||
| - | [[Category: Markley, J | + | [[Category: Markley, J L.]] |
[[Category: Ming, D.]] | [[Category: Ming, D.]] | ||
[[Category: cysteine-stabilized alpha-beta]] | [[Category: cysteine-stabilized alpha-beta]] | ||
[[Category: sweet protein]] | [[Category: sweet protein]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:58:27 2008'' |
Revision as of 09:58, 21 February 2008
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SOLUTION STRUCTURE OF THE SWEET PROTEIN BRAZZEIN, NMR, 43 STRUCTURES
Overview
The fruit of Pentadiplandra brazzeana Baillon contains a small, sweet-tasting protein named brazzein. The structure of brazzein in solution was determined by proton nuclear magnetic resonance spectroscopy at pH 5.2 and 22 degrees C. The brazzein fold, which contains one alpha-helix and three strands of antiparallel beta-sheet, does not resemble that of either of the other two sweet-tasting proteins with known structures, monellin and thaumatin. Instead, the structure of brazzein resembles those of plant gamma-thionins and defensins and arthropod toxins. Sequence comparisons predict that members of a newly-identified family of serine proteinase inhibitors share the brazzein fold.
About this Structure
1BRZ is a Single protein structure of sequence from Pentadiplandra brazzeana. Full crystallographic information is available from OCA.
Reference
Solution structure of the thermostable sweet-tasting protein brazzein., Caldwell JE, Abildgaard F, Dzakula Z, Ming D, Hellekant G, Markley JL, Nat Struct Biol. 1998 Jun;5(6):427-31. PMID:9628478
Page seeded by OCA on Thu Feb 21 11:58:27 2008
