3npc

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Revision as of 20:35, 25 July 2012

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Template:STRUCTURE 3npc

Contents 1 Crystal structure of JNK2 complexed with BIRB796 2 About this Structure 3 See Also 4 Reference

Crystal structure of JNK2 complexed with BIRB796

Template:ABSTRACT PUBMED 20655210

About this Structure

3npc is a 2 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Mitogen-activated protein kinase

Reference

• Kuglstatter A, Ghate M, Tsing S, Villasenor AG, Shaw D, Barnett JW, Browner MF. X-ray crystal structure of JNK2 complexed with the p38alpha inhibitor BIRB796: insights into the rational design of DFG-out binding MAP kinase inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5217-20. Epub 2010 Jul 23. PMID:20655210 doi:10.1016/j.bmcl.2010.06.157